Entity Details

Primary name SCNNB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51168
EntryNameSCNNB_HUMAN
FullNameAmiloride-sensitive sodium channel subunit beta
TaxID9606
Evidenceevidence at protein level
Length640
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesSCNN1B

GO terms

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GOName
GO:0002269 leukocyte activation involved in inflammatory response
GO:0002283 neutrophil activation involved in immune response
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006814 sodium ion transport
GO:0007588 excretion
GO:0009897 external side of plasma membrane
GO:0010467 gene expression
GO:0014824 artery smooth muscle contraction
GO:0015280 ligand-gated sodium channel activity
GO:0016324 apical plasma membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0032094 response to food
GO:0032341 aldosterone metabolic process
GO:0034101 erythrocyte homeostasis
GO:0034220 ion transmembrane transport
GO:0034706 sodium channel complex
GO:0035264 multicellular organism growth
GO:0035725 sodium ion transmembrane transport
GO:0042045 epithelial fluid transport
GO:0042493 response to drug
GO:0050699 WW domain binding
GO:0050891 multicellular organismal water homeostasis
GO:0050909 sensory perception of taste
GO:0055075 potassium ion homeostasis
GO:0055078 sodium ion homeostasis
GO:0070062 extracellular exosome
GO:0070254 mucus secretion
GO:0070944 neutrophil-mediated killing of bacterium
GO:0097274 urea homeostasis
GO:0098797 plasma membrane protein complex
GO:1904045 cellular response to aldosterone

Subcellular Location

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Subcellular Location
Apical cell membrane
Cytoplasmic vesicle membrane

Domains

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DomainNameCategoryType
IPR001873 Epithelial sodium channelFamilyFamily
IPR004724 Epithelial sodium channel, chordatesFamilyFamily
IPR020903 Epithelial sodium channel, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00384 TriamtereneDrugbanksmall molecule
DB00594 AmilorideDrugbanksmall molecule
DB14509 Lithium carbonateDrugbanksmall molecule