Entity Details

Primary name WNT3A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56704
EntryNameWNT3A_HUMAN
FullNameProtein Wnt-3a
TaxID9606
Evidenceevidence at protein level
Length352
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesWNT3A

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0001701 in utero embryonic development
GO:0001819 positive regulation of cytokine production
GO:0001934 positive regulation of protein phosphorylation
GO:0001947 heart looping
GO:0002092 positive regulation of receptor internalization
GO:0003136 negative regulation of heart induction by canonical Wnt signaling pathway
GO:0003713 transcription coactivator activity
GO:0005102 signaling receptor binding
GO:0005109 frizzled binding
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005796 Golgi lumen
GO:0005886 plasma membrane
GO:0007411 axon guidance
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0009986 cell surface
GO:0010387 COP9 signalosome assembly
GO:0010628 positive regulation of gene expression
GO:0010977 negative regulation of neuron projection development
GO:0016055 Wnt signaling pathway
GO:0019904 protein domain specific binding
GO:0021527 spinal cord association neuron differentiation
GO:0021766 hippocampus development
GO:0021846 cell proliferation in forebrain
GO:0021874 Wnt signaling pathway involved in forebrain neuroblast division
GO:0021904 dorsal/ventral neural tube patterning
GO:0030097 hemopoiesis
GO:0030182 neuron differentiation
GO:0030198 extracellular matrix organization
GO:0030666 endocytic vesicle membrane
GO:0030879 mammary gland development
GO:0030890 positive regulation of B cell proliferation
GO:0031901 early endosome membrane
GO:0032092 positive regulation of protein binding
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033278 cell proliferation in midbrain
GO:0034613 cellular protein localization
GO:0035914 skeletal muscle cell differentiation
GO:0036342 post-anal tail morphogenesis
GO:0036465 synaptic vesicle recycling
GO:0039706 co-receptor binding
GO:0042472 inner ear morphogenesis
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045165 cell fate commitment
GO:0045599 negative regulation of fat cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048018 receptor ligand activity
GO:0048103 somatic stem cell division
GO:0048337 positive regulation of mesodermal cell fate specification
GO:0048343 paraxial mesodermal cell fate commitment
GO:0048643 positive regulation of skeletal muscle tissue development
GO:0048697 positive regulation of collateral sprouting in absence of injury
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0050768 negative regulation of neurogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0050807 regulation of synapse organization
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060070 canonical Wnt signaling pathway
GO:0061098 positive regulation of protein tyrosine kinase activity
GO:0061184 positive regulation of dermatome development
GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
GO:0062009 secondary palate development
GO:0070062 extracellular exosome
GO:0070507 regulation of microtubule cytoskeleton organization
GO:0070527 platelet aggregation
GO:0071300 cellular response to retinoic acid
GO:0090245 axis elongation involved in somitogenesis
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0090676 calcium ion transmembrane transport via low voltage-gated calcium channel
GO:0098793 presynapse
GO:0098978 glutamatergic synapse
GO:0099054 presynapse assembly
GO:0099527 postsynapse to nucleus signaling pathway
GO:1901215 negative regulation of neuron death
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1904339 negative regulation of dopaminergic neuron differentiation
GO:1904886 beta-catenin destruction complex disassembly
GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
GO:1905606 regulation of presynapse assembly
GO:1990851 Wnt-Frizzled-LRP5/6 complex
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin
GO:2000081 positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2000347 positive regulation of hepatocyte proliferation
GO:2000727 positive regulation of cardiac muscle cell differentiation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR005817 WntFamilyFamily
IPR009141 Wnt-3 proteinFamilyFamily
IPR018161 Wnt protein, conserved siteSiteConserved site
IPR043158 Wnt, C-terminal domainFamilyHomologous superfamily

Diseases

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