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Entity Details
Primary name
TPM4_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P67936
EntryName
TPM4_HUMAN
FullName
Tropomyosin alpha-4 chain
TaxID
9606
Evidence
evidence at protein level
Length
248
SequenceStatus
complete
DateCreated
1988-04-01
DateModified
2021-06-02
Ontological Relatives
Genes
TPM4
GO terms
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GO
Name
GO:0001649
osteoblast differentiation
GO:0001725
stress fiber
GO:0005509
calcium ion binding
GO:0005829
cytosol
GO:0005856
cytoskeleton
GO:0005862
muscle thin filament tropomyosin
GO:0005884
actin filament
GO:0005925
focal adhesion
GO:0006936
muscle contraction
GO:0007015
actin filament organization
GO:0008307
structural constituent of muscle
GO:0016020
membrane
GO:0030049
muscle filament sliding
GO:0042802
identical protein binding
GO:0042803
protein homodimerization activity
GO:0046982
protein heterodimerization activity
GO:0051015
actin filament binding
GO:0070062
extracellular exosome
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR000533
Tropomyosin
Family
Family
Diseases
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Drugs
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Drug
Name
Source
Type
DB12695
Phenethyl Isothiocyanate
Drugbank
small molecule
Interactions
13 interactions
Interactor
Partner
Sources
Publications
Link
TPM4_HUMAN
PACN1_HUMAN
BioGRID, IntAct
20936779
details
TPM4_HUMAN
SNAPN_HUMAN
BioGRID, IntAct
32296183
details
TPM4_HUMAN
PICK1_HUMAN
BioGRID, IntAct
32296183
details
TPM4_HUMAN
TPM3_HUMAN
BioGRID, IntAct
22939629
32296183
details
TPM4_HUMAN
JERKY_HUMAN
BioGRID, IntAct
32296183
details
TPM4_HUMAN
TPM1_HUMAN
BioGRID, IntAct
22939629
25416956
26186194
28514442
details
TPM4_HUMAN
TRIP6_HUMAN
BioGRID, HPRD
11782456
details
TPM4_HUMAN
LNX1_HUMAN
BioGRID
25416956
details
TPM4_HUMAN
SMUF1_HUMAN
BioGRID
20804422
details
TPM4_HUMAN
NOD2_HUMAN
BioGRID
27812135
details
TPM4_HUMAN
TCRG1_HUMAN
BioGRID, HPRD
15456888
details
TPM4_HUMAN
UNK_HUMAN
BioGRID
29395067
details
TPM4_HUMAN
ISG15_HUMAN
BioGRID
33024031
details
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