Entity Details

Primary name DSG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02413
EntryNameDSG1_HUMAN
FullNameDesmoglein-1
TaxID9606
Evidenceevidence at protein level
Length1049
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesDSG1

GO terms

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GOName
GO:0001533 cornified envelope
GO:0005509 calcium ion binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007043 cell-cell junction assembly
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0009898 cytoplasmic side of plasma membrane
GO:0015643 toxic substance binding
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0030057 desmosome
GO:0031424 keratinization
GO:0032570 response to progesterone
GO:0043312 neutrophil degranulation
GO:0045295 gamma-catenin binding
GO:0050821 protein stabilization
GO:0060135 maternal process involved in female pregnancy
GO:0070268 cornification
GO:0098609 cell-cell adhesion
GO:0101003 ficolin-1-rich granule membrane

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR000233 Cadherin, cytoplasmic domainDomainDomain
IPR002126 Cadherin-likeDomainDomain
IPR009122 Desmosomal cadherinFamilyFamily
IPR009123 DesmogleinFamilyFamily
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR020894 Cadherin conserved siteSiteConserved site
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily

Diseases

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