Entity Details

Primary name FOXM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08050
EntryNameFOXM1_HUMAN
FullNameForkhead box protein M1
TaxID9606
Evidenceevidence at protein level
Length763
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesFOXM1

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001558 regulation of cell growth
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006281 DNA repair
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008284 positive regulation of cell population proliferation
GO:0019901 protein kinase binding
GO:0032873 negative regulation of stress-activated MAPK cascade
GO:0042127 regulation of cell population proliferation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046578 regulation of Ras protein signal transduction
GO:0051726 regulation of cell cycle
GO:0090344 negative regulation of cell aging
GO:2000377 regulation of reactive oxygen species metabolic process
GO:2000781 positive regulation of double-strand break repair

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001766 Fork head domainDomainDomain
IPR018122 Fork head domain conserved site1SiteConserved site
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR042839 Forkhead box protein M1FamilyFamily

Diseases

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Interactions

53 interactions

InteractorPartnerSourcesPublicationsLink
FOXM1_HUMANCCNE1_HUMANBioGRID, MINT15024056 16504183 details
FOXM1_HUMANOS9_HUMANBioGRID, IntAct21988832 details
FOXM1_HUMANBANP_HUMANBioGRID, IntAct21988832 26871637 details
FOXM1_HUMANCTNB1_HUMANBioGRID, IntAct22014570 26912724 details
FOXM1_HUMANCDK4_HUMANBioGRID, IntAct22094256 details
FOXM1_HUMANANR12_HUMANIntAct22094256 details
FOXM1_HUMANCDK6_HUMANBioGRID, IntAct22094256 details
FOXM1_HUMANZBTB3_HUMANIntAct20211142 details
FOXM1_HUMANCHK2_HUMANBioGRID17101782 details
FOXM1_HUMANCDK1_HUMANBioGRID, HPRD15024056 27542221 details
FOXM1_HUMANCDK2_HUMANBioGRID, HPRD15024056 16504183 details
FOXM1_HUMANSP1_HUMANBioGRID23635401 details
FOXM1_HUMANUBC9_HUMANBioGRID24362530 details
FOXM1_HUMANSUMO1_HUMANBioGRID24362530 details
FOXM1_HUMANSMAD3_HUMANBioGRID24382352 details
FOXM1_HUMANOTUB1_HUMANBioGRID26148240 27167337 31879190 details
FOXM1_HUMANDCAF1_HUMANBioGRID28416635 details
FOXM1_HUMANSIR1_HUMANBioGRID27542221 details
FOXM1_HUMANHIF1A_HUMANBioGRID19097132 details
FOXM1_HUMANUBP21_HUMANBioGRID30865895 details
FOXM1_HUMANUCHL3_HUMANBioGRID31598398 details
FOXM1_HUMANFOXO3_HUMANIntAct16809346 details
FOXM1_HUMANTF7L2_HUMANIntAct22014570 details
FOXM1_HUMANHS90B_HUMANIntAct22939624 details
FOXM1_HUMANCDC37_HUMANIntAct22939624 details
FOXM1_HUMANGORS2_HUMANMINT23241949 details
FOXM1_HUMANSYIM_HUMANMINT25609649 details
FOXM1_HUMANMEN1_HUMANMINT25609649 details
FOXM1_HUMANFBXL2_HUMANBioGRID, MINT26790640 31679690 31953162 details
FOXM1_HUMANTOP2A_HUMANDIP15965487 details
FOXM1_HUMANCCNB1_HUMANBioGRID15024056 27542221 details
FOXM1_HUMANMPIP2_HUMANBioGRID15024056 details
FOXM1_HUMANRB_HUMANBioGRID15024056 details
FOXM1_HUMANCBP_HUMANBioGRID, HPRD15024056 27542221 details
FOXM1_HUMANCDC27_HUMANBioGRID18573889 32076268 details
FOXM1_HUMANFZR1_HUMANBioGRID18573889 18758239 24362530 details
FOXM1_HUMANBCL6_HUMANBioGRID17828269 details
FOXM1_HUMANHS90A_HUMANBioGRID22939624 details
FOXM1_HUMANGSK3A_HUMANBioGRID26912724 details
FOXM1_HUMANGSK3B_HUMANBioGRID26912724 details
FOXM1_HUMANAXIN1_HUMANBioGRID26912724 details
FOXM1_HUMANFBXW7_HUMANBioGRID26912724 details
FOXM1_HUMANUBP5_HUMANBioGRID26912724 28807830 details
FOXM1_HUMANFBX31_HUMANBioGRID27568981 details
FOXM1_HUMANRN168_HUMANBioGRID27526106 details
FOXM1_HUMANRNF8_HUMANBioGRID27526106 details
FOXM1_HUMANEZH2_HUMANBioGRID27303043 details
FOXM1_HUMANEP300_HUMANBioGRID27542221 details
FOXM1_HUMANPLK1_HUMANBioGRID27542221 details
FOXM1_HUMANOTU7B_HUMANBioGRID29973362 details
FOXM1_HUMANCSN5_HUMANBioGRID30352219 details
FOXM1_HUMANLZTS2_HUMANBioGRID29395067 details
FOXM1_HUMANSTAT3_HUMANHPRD11861839 details