Entity Details

Primary name HPSE
Entity type gene
Source Source Link

Details

PrimaryID10855
RefseqGeneNG_028037
SymbolHPSE
Nameheparanase
Chromosome4
Location4q21.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHPSE_HUMAN

GO terms

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GOName
GO:0004566 beta-glucuronidase activity
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0006027 glycosaminoglycan catabolic process
GO:0006029 proteoglycan metabolic process
GO:0007160 cell-matrix adhesion
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0030194 positive regulation of blood coagulation
GO:0030200 heparan sulfate proteoglycan catabolic process
GO:0030305 heparanase activity
GO:0031012 extracellular matrix
GO:0033690 positive regulation of osteoblast proliferation
GO:0035580 specific granule lumen
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0045121 membrane raft
GO:0045545 syndecan binding
GO:0051797 regulation of hair follicle development
GO:0051798 positive regulation of hair follicle development
GO:0051897 positive regulation of protein kinase B signaling
GO:0060055 angiogenesis involved in wound healing
GO:0061042 vascular wound healing
GO:1904974 heparanase complex

Diseases

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Interactions

25 interactions

InteractorPartnerSourcesPublicationsLink
HPSEHPSEBioGRID, HPRD12927802 details
HPSERETREG2BioGRID, IntAct26496610 details
HPSEERBB2BioGRID, IntAct26496610 details
HPSENIPSNAP1BioGRID, IntAct26496610 details
HPSEFBXO7BioGRID, IntAct26496610 details
HPSESCGB2A2BioGRID, IntAct28514442 details
HPSEDNAJA4BioGRID, IntAct28514442 details
HPSEOS9BioGRID, IntAct28514442 details
HPSEH2BC9BioGRID, IntAct30021884 details
HPSEBAG5BioGRID, IntAct30833792 details
HPSESUN2BioGRID, IntAct30833792 details
HPSEHSPH1BioGRID, IntAct30833792 details
HPSEHSPA2BioGRID, IntAct30833792 details
HPSEPSMB3BioGRID, IntAct30833792 details
HPSEHSPA4BioGRID, IntAct30833792 details
HPSESTIP1BioGRID, IntAct30833792 details
HPSEDNAJA1BioGRID, IntAct30833792 details
HPSEDNAJB1BioGRID, IntAct30833792 details
HPSEBAG2BioGRID, IntAct30833792 details
HPSEDNAJA2BioGRID, IntAct30833792 details
HPSECLIC1BioGRID, IntAct30833792 details
HPSEDNAJC7BioGRID30833792 details
HPSESTUB1BioGRID30833792 details
HPSEKIF14BioGRID31586073 details
HPSEKIF20ABioGRID31586073 details