Entity Details

Primary name MAP3K8
Entity type gene
Source Source Link

Details

PrimaryID1326
RefseqGeneNG_029984
SymbolMAP3K8
Namemitogen-activated protein kinase kinase kinase 8
Chromosome10
Location10p11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-15
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsM3K8_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0007049 cell cycle
GO:0031295 T cell costimulation
GO:0051403 stress-activated MAPK cascade
GO:0070498 interleukin-1-mediated signaling pathway
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Diseases

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Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
MAP3K8TNIP2BioGRID, HPRD, IntAct14743216 15169888 25852190 29084252 details
MAP3K8NFKB1BioGRID, HPRD, IntAct, MINT12832462 14743216 15169888 16291755 21988832 25609649 25852190 29084252 9950430 details
MAP3K8RELABioGRID, HPRD, IntAct14743216 25331947 25852190 29084252 9950430 details
MAP3K8STIP1BioGRID, IntAct21988832 details
MAP3K8ACY3BioGRID, IntAct21988832 details
MAP3K8MAP2K1BioGRID, IntAct12832462 16291755 8631303 details
MAP3K8PIN1IntAct24265246 details
MAP3K8CHUKBioGRID, HPRD10072079 details
MAP3K8MAP2K4BioGRID, HPRD8631303 details
MAP3K8AKT1BioGRID, HPRD12138205 details
MAP3K8HSPA1LIntAct14743216 details
MAP3K8HSPA5IntAct14743216 details
MAP3K8HSPA9IntAct14743216 details
MAP3K8EPPK1IntAct14743216 details
MAP3K8MAP3K8IntAct14743216 details
MAP3K8EEF1A2IntAct14743216 details
MAP3K8RUVBL1IntAct14743216 details
MAP3K8LGALS3BPIntAct14743216 details
MAP3K8CLTCIntAct14743216 details
MAP3K8HSPA8IntAct14743216 details
MAP3K8CALM1IntAct14743216 details
MAP3K8CALM2IntAct14743216 details
MAP3K8CALM3IntAct14743216 details
MAP3K8TUBBIntAct14743216 details
MAP3K8PFKLIntAct14743216 details
MAP3K8TUBB4AIntAct14743216 details
MAP3K8ACTL6AIntAct14743216 details
MAP3K8SPTBN1IntAct14743216 details
MAP3K8DSPIntAct14743216 details
MAP3K8HSP90AA1BioGRID, IntAct14743216 22939624 details
MAP3K8TUBA3DIntAct14743216 details
MAP3K8TUBA3CIntAct14743216 details
MAP3K8HSP90AB1IntAct14743216 22939624 details
MAP3K8RELBioGRID, HPRD, IntAct14743216 9950430 details
MAP3K8KSR2BioGRID12975377 details
MAP3K8MAP3K14BioGRID, HPRD10072079 11278268 9742107 details
MAP3K8TRAF2BioGRID, HPRD11932422 15670770 16291755 details
MAP3K8CD40BioGRID, HPRD15670770 details
MAP3K8TRAF6BioGRID, HPRD15670770 details
MAP3K8TAB2BioGRID15670770 details
MAP3K8RIPK1BioGRID, HPRD16291755 details
MAP3K8BMPR2HPRD15188402 details
MAP3K8NFKB2BioGRID, HPRD, IntAct14743216 25852190 details
MAP3K8XPO1BioGRID26673895 details