Entity Details

Primary name IL18R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13478
EntryNameIL18R_HUMAN
FullNameInterleukin-18 receptor 1
TaxID9606
Evidenceevidence at protein level
Length541
SequenceStatuscomplete
DateCreated2002-12-06
DateModified2021-06-02

Ontological Relatives

GenesIL18R1

GO terms

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GOName
GO:0004908 interleukin-1 receptor activity
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007165 signal transduction
GO:0030101 natural killer cell activation
GO:0032729 positive regulation of interferon-gamma production
GO:0035655 interleukin-18-mediated signaling pathway
GO:0038023 signaling receptor activity
GO:0042007 interleukin-18 binding
GO:0042008 interleukin-18 receptor activity
GO:0045063 T-helper 1 cell differentiation
GO:0045092 interleukin-18 receptor complex
GO:0050135 NAD(P)+ nucleosidase activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:0071345 cellular response to cytokine stimulus
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000556 positive regulation of T-helper 1 cell cytokine production

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000157 Toll/interleukin-1 receptor homology (TIR) domainDomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR004074 Interleukin-1 receptor type I/IIFamilyFamily
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015621 Interleukin-1 receptor familyFamilyFamily
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions