Entity Details

Primary name DAB2IP
Entity type gene
Source Source Link

Details

PrimaryID153090
RefseqGene
SymbolDAB2IP
NameDAB2 interacting protein
Chromosome9
Location9q33.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-01-23
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsDAB2P_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000165 MAPK cascade
GO:0000185 obsolete activation of MAPKKK activity
GO:0001525 angiogenesis
GO:0001933 negative regulation of protein phosphorylation
GO:0005096 GTPase activator activity
GO:0005123 death receptor binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0007049 cell cycle
GO:0007252 I-kappaB phosphorylation
GO:0007257 obsolete activation of JUN kinase activity
GO:0008285 negative regulation of cell population proliferation
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0010596 negative regulation of endothelial cell migration
GO:0010633 negative regulation of epithelial cell migration
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010976 positive regulation of neuron projection development
GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling
GO:0016525 negative regulation of angiogenesis
GO:0017124 SH3 domain binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0021814 cell motility involved in cerebral cortex radial glia guided migration
GO:0021819 layer formation in cerebral cortex
GO:0030139 endocytic vesicle
GO:0030424 axon
GO:0030425 dendrite
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0032809 neuronal cell body membrane
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway
GO:0034260 negative regulation of GTPase activity
GO:0034620 cellular response to unfolded protein
GO:0035148 tube formation
GO:0035591 signaling adaptor activity
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding
GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway
GO:0038026 reelin-mediated signaling pathway
GO:0040008 regulation of growth
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043087 regulation of GTPase activity
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043184 vascular endothelial growth factor receptor 2 binding
GO:0043254 regulation of protein-containing complex assembly
GO:0043407 negative regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043507 positive regulation of JUN kinase activity
GO:0043547 positive regulation of GTPase activity
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity
GO:0044257 cellular protein catabolic process
GO:0044300 cerebellar mossy fiber
GO:0044301 climbing fiber
GO:0044877 protein-containing complex binding
GO:0045087 innate immune response
GO:0045296 cadherin binding
GO:0045732 positive regulation of protein catabolic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046330 positive regulation of JNK cascade
GO:0046580 negative regulation of Ras protein signal transduction
GO:0048147 negative regulation of fibroblast proliferation
GO:0048812 neuron projection morphogenesis
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051721 protein phosphatase 2A binding
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0070317 negative regulation of G0 to G1 transition
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071222 cellular response to lipopolysaccharide
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0071889 14-3-3 protein binding
GO:0071901 negative regulation of protein serine/threonine kinase activity
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0072577 endothelial cell apoptotic process
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090129 positive regulation of synapse maturation
GO:1900006 positive regulation of dendrite development
GO:1900744 regulation of p38MAPK cascade
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
GO:1901800 positive regulation of proteasomal protein catabolic process
GO:1903363 negative regulation of cellular protein catabolic process
GO:1903896 positive regulation of IRE1-mediated unfolded protein response
GO:1990032 parallel fiber
GO:1990597 AIP1-IRE1 complex
GO:2001224 positive regulation of neuron migration
GO:2001235 positive regulation of apoptotic signaling pathway

Diseases

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Interactions

55 interactions

InteractorPartnerSourcesPublicationsLink
DAB2IPMAP3K5BioGRID, HPRD, UniProt12813029 15310755 17389591 19903888 24985705 details
DAB2IPANKS1ABioGRID, IntAct28514442 32296183 details
DAB2IPDAB2BioGRID11812785 details
DAB2IPYWHAQBioGRID17389591 details
DAB2IPPIK3R1BioGRID19903888 details
DAB2IPAKT1BioGRID19903888 24912918 details
DAB2IPDAB2IPUniProt12813029 details
DAB2IPCBY1BioGRID, IntAct27173435 unassigned1312 details
DAB2IPGSK3BDIP20080667 details
DAB2IPAXIN1DIP20080667 details
DAB2IPSMARCA2MINT21653829 details
DAB2IPTRAF2BioGRID15310755 17389591 24912918 details
DAB2IPRIPK1BioGRID15310755 17389591 details
DAB2IPTNFRSF1ABioGRID15310755 details
DAB2IPTRADDBioGRID15310755 details
DAB2IPHRASBioGRID24912918 details
DAB2IPCUL1BioGRID24912918 details
DAB2IPCUL4ABioGRID24912918 details
DAB2IPSKP1BioGRID24912918 details
DAB2IPRBX1BioGRID24912918 details
DAB2IPFBXW7BioGRID24912918 details
DAB2IPDAB1HPRD11812785 details
DAB2IPPACC1BioGRID, IntAct28514442 details
DAB2IPCD83BioGRID, IntAct28514442 details
DAB2IPRFPL3BioGRID, IntAct26186194 28514442 details
DAB2IPCLIP1BioGRID, IntAct28514442 details
DAB2IPCGNBioGRID, IntAct28514442 details
DAB2IPSNX17BioGRID, IntAct28514442 details
DAB2IPMCCBioGRID, IntAct28514442 details
DAB2IPYWHABIntAct28514442 details
DAB2IPYWHAGIntAct28514442 details
DAB2IPYWHAHIntAct28514442 details
DAB2IPYWHAEBioGRID, IntAct31980649 details
DAB2IPTP53BioGRID20308539 details
DAB2IPTP63BioGRID20308539 details
DAB2IPTP73BioGRID20308539 details
DAB2IPNTRK1BioGRID25921289 details
DAB2IPXPO1BioGRID26673895 details
DAB2IPEXOSC9BioGRID26496610 details
DAB2IPRAB4BBioGRID26496610 details
DAB2IPIWS1BioGRID26496610 details
DAB2IPUGGT1BioGRID26496610 details
DAB2IPRNASEH2BBioGRID26496610 details
DAB2IPCDH1BioGRID25468996 details
DAB2IPCTDSPLBioGRID27880917 details
DAB2IPNRASBioGRID30639242 details
DAB2IPC11orf52BioGRID34079125 details
DAB2IPKRASBioGRID34079125 details
DAB2IPLYNBioGRID34079125 details
DAB2IPOCLNBioGRID34079125 details
DAB2IPRAB35BioGRID34079125 details
DAB2IPRHOBBioGRID34079125 details
DAB2IPERGIntAct20478527 details
DAB2IPTRIM25BioGRID29117863 details
DAB2IPVIRMABioGRID29507755 details