Entity Details

Primary name EDN1
Entity type gene
Source Source Link

Details

PrimaryID1906
RefseqGeneNG_016196
SymbolEDN1
Nameendothelin 1
Chromosome6
Location6p24.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-14
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsEDN1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001516 prostaglandin biosynthetic process
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001701 in utero embryonic development
GO:0001821 histamine secretion
GO:0003100 regulation of systemic arterial blood pressure by endothelin
GO:0005125 cytokine activity
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006874 cellular calcium ion homeostasis
GO:0006885 regulation of pH
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007507 heart development
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0007589 body fluid secretion
GO:0008284 positive regulation of cell population proliferation
GO:0009953 dorsal/ventral pattern formation
GO:0010193 response to ozone
GO:0010259 multicellular organism aging
GO:0010460 positive regulation of heart rate
GO:0010595 positive regulation of endothelial cell migration
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0010629 negative regulation of gene expression
GO:0010827 regulation of glucose transmembrane transport
GO:0014032 neural crest cell development
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0014823 response to activity
GO:0014824 artery smooth muscle contraction
GO:0014826 vein smooth muscle contraction
GO:0019229 regulation of vasoconstriction
GO:0019233 sensory perception of pain
GO:0019722 calcium-mediated signaling
GO:0030072 peptide hormone secretion
GO:0030133 transport vesicle
GO:0030185 nitric oxide transport
GO:0030195 negative regulation of blood coagulation
GO:0030335 positive regulation of cell migration
GO:0031583 phospholipase D-activating G protein-coupled receptor signaling pathway
GO:0031707 endothelin A receptor binding
GO:0031708 endothelin B receptor binding
GO:0032269 negative regulation of cellular protein metabolic process
GO:0032308 positive regulation of prostaglandin secretion
GO:0032496 response to lipopolysaccharide
GO:0033093 Weibel-Palade body
GO:0033574 response to testosterone
GO:0034392 negative regulation of smooth muscle cell apoptotic process
GO:0034696 response to prostaglandin F
GO:0035094 response to nicotine
GO:0035690 cellular response to drug
GO:0035810 positive regulation of urine volume
GO:0035815 positive regulation of renal sodium excretion
GO:0035994 response to muscle stretch
GO:0042045 epithelial fluid transport
GO:0042310 vasoconstriction
GO:0042313 protein kinase C deactivation
GO:0042474 middle ear morphogenesis
GO:0042482 positive regulation of odontogenesis
GO:0042554 superoxide anion generation
GO:0043179 rhythmic excitation
GO:0043200 response to amino acid
GO:0043406 positive regulation of MAP kinase activity
GO:0043507 positive regulation of JUN kinase activity
GO:0044321 response to leptin
GO:0045178 basal part of cell
GO:0045321 leukocyte activation
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045793 positive regulation of cell size
GO:0045840 positive regulation of mitotic nuclear division
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045987 positive regulation of smooth muscle contraction
GO:0046887 positive regulation of hormone secretion
GO:0046888 negative regulation of hormone secretion
GO:0048016 inositol phosphate-mediated signaling
GO:0048237 rough endoplasmic reticulum lumen
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051216 cartilage development
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process
GO:0051899 membrane depolarization
GO:0051930 regulation of sensory perception of pain
GO:0060137 maternal process involved in parturition
GO:0060298 positive regulation of sarcomere organization
GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
GO:0070101 positive regulation of chemokine-mediated signaling pathway
GO:0071277 cellular response to calcium ion
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071375 cellular response to peptide hormone stimulus
GO:0071385 cellular response to glucocorticoid stimulus
GO:0071389 cellular response to mineralocorticoid stimulus
GO:0071398 cellular response to fatty acid
GO:0071456 cellular response to hypoxia
GO:0071548 response to dexamethasone
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0086100 endothelin receptor signaling pathway
GO:0090023 positive regulation of neutrophil chemotaxis
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1902074 response to salt
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:2000273 positive regulation of signaling receptor activity

Diseases

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Interactions

13 interactions