Entity Details

Primary name DSG2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14126
EntryNameDSG2_HUMAN
FullNameDesmoglein-2
TaxID9606
Evidenceevidence at protein level
Length1118
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesDSG2

GO terms

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GOName
GO:0001533 cornified envelope
GO:0002934 desmosome organization
GO:0003165 Purkinje myocyte development
GO:0005509 calcium ion binding
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0009986 cell surface
GO:0014704 intercalated disc
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0030054 cell junction
GO:0030057 desmosome
GO:0031424 keratinization
GO:0032570 response to progesterone
GO:0043231 intracellular membrane-bounded organelle
GO:0050839 cell adhesion molecule binding
GO:0060135 maternal process involved in female pregnancy
GO:0070062 extracellular exosome
GO:0070268 cornification
GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication
GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
GO:0086091 regulation of heart rate by cardiac conduction
GO:0098609 cell-cell adhesion
GO:0098911 regulation of ventricular cardiac muscle cell action potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR002126 Cadherin-likeDomainDomain
IPR009122 Desmosomal cadherinFamilyFamily
IPR009123 DesmogleinFamilyFamily
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR020894 Cadherin conserved siteSiteConserved site
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily

Diseases

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