Entity Details

Primary name FGFR2
Entity type gene
Source Source Link

Details

PrimaryID2263
RefseqGeneNG_012449
SymbolFGFR2
Namefibroblast growth factor receptor 2
Chromosome10
Location10q26.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsFGFR2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000165 MAPK cascade
GO:0001525 angiogenesis
GO:0001657 ureteric bud development
GO:0001701 in utero embryonic development
GO:0001837 epithelial to mesenchymal transition
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0003148 outflow tract septum morphogenesis
GO:0003149 membranous septum morphogenesis
GO:0003416 endochondral bone growth
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005938 cell cortex
GO:0006915 apoptotic process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007267 cell-cell signaling
GO:0007275 multicellular organism development
GO:0007409 axonogenesis
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0008589 regulation of smoothened signaling pathway
GO:0009791 post-embryonic development
GO:0009880 embryonic pattern specification
GO:0009887 animal organ morphogenesis
GO:0009986 cell surface
GO:0010518 positive regulation of phospholipase activity
GO:0010839 negative regulation of keratinocyte proliferation
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016331 morphogenesis of embryonic epithelium
GO:0017134 fibroblast growth factor binding
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0021769 orbitofrontal cortex development
GO:0021847 ventricular zone neuroblast division
GO:0021860 pyramidal neuron development
GO:0022612 gland morphogenesis
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030282 bone mineralization
GO:0030324 lung development
GO:0030855 epithelial cell differentiation
GO:0030901 midbrain development
GO:0030916 otic vesicle formation
GO:0031069 hair follicle morphogenesis
GO:0031410 cytoplasmic vesicle
GO:0032496 response to lipopolysaccharide
GO:0032808 lacrimal gland development
GO:0033674 positive regulation of kinase activity
GO:0033688 regulation of osteoblast proliferation
GO:0035265 organ growth
GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell
GO:0035603 fibroblast growth factor receptor signaling pathway involved in hemopoiesis
GO:0035604 fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
GO:0042060 wound healing
GO:0042472 inner ear morphogenesis
GO:0042476 odontogenesis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043235 receptor complex
GO:0043410 positive regulation of MAPK cascade
GO:0045165 cell fate commitment
GO:0045471 response to ethanol
GO:0045667 regulation of osteoblast differentiation
GO:0045787 positive regulation of cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046777 protein autophosphorylation
GO:0048286 lung alveolus development
GO:0048333 mesodermal cell differentiation
GO:0048557 embryonic digestive tract morphogenesis
GO:0048562 embryonic organ morphogenesis
GO:0048565 digestive tract development
GO:0048568 embryonic organ development
GO:0048608 reproductive structure development
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048705 skeletal system morphogenesis
GO:0048730 epidermis morphogenesis
GO:0048755 branching morphogenesis of a nerve
GO:0048762 mesenchymal cell differentiation
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051150 regulation of smooth muscle cell differentiation
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060076 excitatory synapse
GO:0060174 limb bud formation
GO:0060348 bone development
GO:0060349 bone morphogenesis
GO:0060442 branching involved in prostate gland morphogenesis
GO:0060445 branching involved in salivary gland morphogenesis
GO:0060449 bud elongation involved in lung branching
GO:0060463 lung lobe morphogenesis
GO:0060484 lung-associated mesenchyme development
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060512 prostate gland morphogenesis
GO:0060523 prostate epithelial cord elongation
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0060595 fibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0060601 lateral sprouting from an epithelium
GO:0060615 mammary gland bud formation
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis
GO:0060667 branch elongation involved in salivary gland morphogenesis
GO:0060670 branching involved in labyrinthine layer morphogenesis
GO:0060688 regulation of morphogenesis of a branching structure
GO:0060915 mesenchymal cell differentiation involved in lung development
GO:0060916 mesenchymal cell proliferation involved in lung development
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071300 cellular response to retinoic acid
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0090263 positive regulation of canonical Wnt signaling pathway

Diseases

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Interactions

106 interactions

InteractorPartnerSourcesPublicationsLink
FGFR2FGF1BioGRID, DIP, IntAct, MINT10618369 11069186 11714710 1697263 18199118 22955284 25241761 7499435 8576175 9700203 details
FGFR2FGF2BioGRID, IntAct, UniProt10830168 11390973 1697263 17981115 18199118 26267536 28514442 9700203 details
FGFR2FGF10BioGRID, IntAct12591959 18199118 25241761 9582367 details
FGFR2PPM1ABioGRID, IntAct21988832 details
FGFR2ANOS1BioGRID, IntAct19696444 details
FGFR2GRB2DIP, IntAct22726438 24440983 details
FGFR2FGFR2BioGRID, DIP, IntAct10830168 11069186 12887919 19060208 22726438 9700203 details
FGFR2FGF7BioGRID, IntAct11714710 1309608 7499435 9582367 details
FGFR2CCN2MINT23142580 details
FGFR2PLCG1BioGRID, DIP, IntAct15629145 24440983 25241761 details
FGFR2FGF8BioGRID, IntAct18199118 25241761 details
FGFR2FGF5BioGRID, IntAct18199118 25241761 details
FGFR2BEX1BioGRID, MINT25640309 details
FGFR2BEX2BioGRID, MINT25640309 details
FGFR2ERRFI1BioGRID, MINT25640309 details
FGFR2GLCEBioGRID, MINT25640309 details
FGFR2HOXC6BioGRID, MINT25640309 details
FGFR2MTA3BioGRID, MINT25640309 details
FGFR2PDLIM2BioGRID, MINT25640309 details
FGFR2RASL10BBioGRID, MINT25640309 details
FGFR2S100A14BioGRID, MINT25640309 details
FGFR2RHOBTB2BioGRID, MINT25640309 details
FGFR2TFF1BioGRID, MINT25640309 details
FGFR2LRRK1BioGRID, IntAct24947832 29513927 details
FGFR2FGFR3BioGRID, DIP, IntAct23972473 28514442 details
FGFR2DUSP14BioGRID, MINT28065597 details
FGFR2CTDSPLBioGRID, MINT28065597 details
FGFR2CTDSP1BioGRID, MINT28065597 details
FGFR2MTMR3BioGRID, MINT28065597 details
FGFR2PTPRRBioGRID, MINT28065597 details
FGFR2PTPN6BioGRID, MINT12887919 28065597 details
FGFR2PTPN11BioGRID, MINT28065597 details
FGFR2PTPN12BioGRID, MINT28065597 details
FGFR2FGF4IntAct9700203 details
FGFR2NEDD4BioGRID19953087 details
FGFR2APPBioGRID21832049 details
FGFR2FGF3BioGRID18199118 details
FGFR2FGF6BioGRID18199118 details
FGFR2FGF9BioGRID18199118 details
FGFR2FGF17BioGRID18199118 details
FGFR2NECTIN1BioGRID22955284 details
FGFR2FBXO7BioGRID27503909 details
FGFR2SHC1BioGRID18840094 details
FGFR2ERBB2BioGRID30898150 details
FGFR2YWHAZMINT18332103 details
FGFR2LAPTM4BIntAct25594178 details
FGFR2MMP14DIP20798051 details
FGFR2PIK3R1BioGRID18374639 details
FGFR2ITGA5BioGRID15728256 details
FGFR2STAT3BioGRID20388777 details
FGFR2PGRBioGRID21464042 details
FGFR2STAT5ABioGRID21464042 details
FGFR2STAT5BBioGRID21464042 details
FGFR2FRS2BioGRID15629145 21596750 details
FGFR2CBLBioGRID15190072 details
FGFR2LYNBioGRID15190072 details
FGFR2FYNBioGRID15190072 details
FGFR2HGSBioGRID19362549 details
FGFR2EPHA4BioGRID16365308 details
FGFR2SRCBioGRID18840094 details
FGFR2KLBBioGRID17623664 details
FGFR2IWS1BioGRID24462114 details
FGFR2SETD2BioGRID24462114 details
FGFR2MORF4L1BioGRID24462114 details
FGFR2PTBP1BioGRID24462114 details
FGFR2FGF23BioGRID, IntAct25241761 details
FGFR2PKMIntAct24606918 details
FGFR2TMEM30BBioGRID, IntAct28514442 details
FGFR2TSPAN3BioGRID, IntAct26186194 28514442 details
FGFR2SLC9A6BioGRID, IntAct28514442 details
FGFR2CD44BioGRID, IntAct28514442 details
FGFR2FAM171BBioGRID, IntAct28514442 details
FGFR2SIGLECL1BioGRID, IntAct28514442 details
FGFR2CCDC120BioGRID, IntAct28514442 details
FGFR2SDC2BioGRID, IntAct28514442 details
FGFR2MRAP2BioGRID, IntAct28514442 details
FGFR2LITAFBioGRID, IntAct28514442 details
FGFR2FCGRTBioGRID, IntAct28514442 details
FGFR2RAET1EBioGRID, IntAct28514442 details
FGFR2LRRIQ1BioGRID, IntAct28514442 details
FGFR2CD83BioGRID, IntAct28514442 details
FGFR2DNAJC30BioGRID, IntAct28514442 details
FGFR2SNX24BioGRID, IntAct28514442 details
FGFR2KIDINS220BioGRID, IntAct28514442 details
FGFR2XPR1BioGRID, IntAct28514442 details
FGFR2BCL11ABioGRID, IntAct28514442 details
FGFR2CEP295BioGRID, IntAct28514442 details
FGFR2PKP4BioGRID, IntAct28514442 details
FGFR2SNX22BioGRID, IntAct28514442 details
FGFR2UBXN4BioGRID, IntAct28514442 details
FGFR2IP6K1BioGRID, IntAct28514442 details
FGFR2CHERPBioGRID, IntAct28514442 details
FGFR2IFFO2BioGRID, IntAct28514442 details
FGFR2RPS6KA1BioGRID, IntAct28514442 details
FGFR2RPS6KA2BioGRID, IntAct28514442 details
FGFR2GAPVD1BioGRID, IntAct28514442 details
FGFR2UBE4ABioGRID, IntAct28514442 details
FGFR2GOLGA3BioGRID, IntAct28514442 details
FGFR2RPS6KA3BioGRID, IntAct28514442 details
FGFR2FGFR1BioGRID, IntAct28514442 details
FGFR2TIMP1BioGRID, IntAct28514442 details
FGFR2U2SURPBioGRID, IntAct28514442 details
FGFR2C8orf74BioGRID, IntAct26186194 28514442 details
FGFR2HEXIM1BioGRID29845934 details
FGFR2LARP7BioGRID29845934 details
FGFR2DCAF4BioGRID30945288 details