Entity Details

Primary name GRB7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14451
EntryNameGRB7_HUMAN
FullNameGrowth factor receptor-bound protein 7
TaxID9606
Evidenceevidence at protein level
Length532
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesGRB7

GO terms

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GOName
GO:0003723 RNA binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007411 axon guidance
GO:0010494 cytoplasmic stress granule
GO:0017148 negative regulation of translation
GO:0019901 protein kinase binding
GO:0030335 positive regulation of cell migration
GO:0034063 stress granule assembly
GO:0035091 phosphatidylinositol binding
GO:0038128 ERBB2 signaling pathway
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0050900 leukocyte migration

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic granule

Domains

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DomainNameCategoryType
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000980 SH2 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015042 BPS (Between PH and SH2) domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035032 Growth factor receptor-bound protein 7FamilyFamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR039664 GRB/APBB1IPFamilyFamily
IPR039665 APBB1IP, PH domainDomainDomain

Diseases

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Interactions

65 interactions

InteractorPartnerSourcesPublicationsLink
GRB7_HUMANERBB3_HUMANBioGRID, HPRD, IntAct, MINT16273093 22973453 24189400 9516479 details
GRB7_HUMANERBB2_HUMANBioGRID, HPRD, MINT, UniProt12061724 12975581 16273093 17875712 22973453 7907978 9079677 details
GRB7_HUMANRND1_HUMANBioGRID, HPRD, UniProt10664463 details
GRB7_HUMANLY66F_HUMANBioGRID, HPRD, MINT12852788 details
GRB7_HUMANKIT_HUMANBioGRID, HPRD, IntAct, MINT10377264 12444928 24728074 details
GRB7_HUMANPGFRB_HUMANBioGRID, HPRD, MINT8940081 details
GRB7_HUMANGRB7_HUMANBioGRID, UniProt15841400 31980649 details
GRB7_HUMANEPHB1_HUMANBioGRID, UniProt12223469 details
GRB7_HUMANHAX1_HUMANUniProt20665473 details
GRB7_HUMANA1BG_HUMANBioGRID, MINT21900206 details
GRB7_HUMANAGAP1_HUMANBioGRID, MINT21900206 details
GRB7_HUMANATPB_HUMANBioGRID, MINT21900206 details
GRB7_HUMANCPNE6_HUMANBioGRID, MINT21900206 details
GRB7_HUMANDOCK7_HUMANBioGRID, MINT21900206 details
GRB7_HUMANDC1I1_HUMANBioGRID, MINT21900206 details
GRB7_HUMANFIBB_HUMANBioGRID, MINT21900206 details
GRB7_HUMANFAD1_HUMANBioGRID, MINT21900206 details
GRB7_HUMANGBB2_HUMANBioGRID, MINT21900206 details
GRB7_HUMANECHB_HUMANBioGRID, MINT21900206 details
GRB7_HUMANKMT2B_HUMANBioGRID, MINT21900206 details
GRB7_HUMANMSH2_HUMANBioGRID, MINT21900206 details
GRB7_HUMANODPB_HUMANBioGRID, MINT21900206 details
GRB7_HUMANPHAX_HUMANBioGRID, MINT21900206 details
GRB7_HUMANKPYM_HUMANBioGRID, IntAct, MINT21900206 24606918 details
GRB7_HUMANRS2_HUMANBioGRID, MINT21900206 details
GRB7_HUMANSETB1_HUMANBioGRID, MINT21900206 details
GRB7_HUMANTLE1_HUMANBioGRID, MINT21900206 details
GRB7_HUMANTYB4_HUMANBioGRID, MINT21900206 details
GRB7_HUMANZBT16_HUMANBioGRID, MINT21900206 details
GRB7_HUMANANDR_HUMANBioGRID, IntAct24728074 details
GRB7_HUMANMET_HUMANBioGRID, IntAct24728074 details
GRB7_HUMANFAK1_HUMANBioGRID, IntAct10446223 11119718 25814554 details
GRB7_HUMANOLIG1_HUMANBioGRID, IntAct25814554 details
GRB7_HUMANZNHI1_HUMANBioGRID, IntAct25814554 details
GRB7_HUMANLAX1_HUMANBioGRID, IntAct25416956 31515488 32296183 details
GRB7_HUMANKCTD6_HUMANBioGRID, IntAct25416956 32296183 details
GRB7_HUMANTRI36_HUMANBioGRID, IntAct25416956 details
GRB7_HUMANSTAC3_HUMANBioGRID, IntAct32296183 details
GRB7_HUMANPICK1_HUMANBioGRID, IntAct32296183 details
GRB7_HUMANHTF4_HUMANBioGRID, IntAct32296183 details
GRB7_HUMANTGM5_HUMANBioGRID, IntAct32296183 details
GRB7_HUMANTRI43_HUMANBioGRID, IntAct32296183 details
GRB7_HUMANUBP2_HUMANBioGRID, IntAct32296183 details
GRB7_HUMANF124B_HUMANBioGRID, IntAct32296183 details
GRB7_HUMANCRERF_HUMANBioGRID, IntAct32296183 details
GRB7_HUMANERBB4_HUMANBioGRID, IntAct22973453 29290818 details
GRB7_HUMANRET_HUMANBioGRID, HPRD8631863 details
GRB7_HUMANINSR_HUMANBioGRID, HPRD10803466 details
GRB7_HUMANCALM1_HUMANBioGRID, HPRD15806159 details
GRB7_HUMANCALM2_HUMANBioGRID, HPRD15806159 details
GRB7_HUMANCALM3_HUMANBioGRID, HPRD15806159 details
GRB7_HUMANGGYF2_HUMANBioGRID16037382 details
GRB7_HUMANSHC1_HUMANBioGRID, HPRD7907978 8940081 details
GRB7_HUMANFCHO1_HUMANBioGRID32296183 details
GRB7_HUMANEGFR_HUMANBioGRID, HPRD22973453 9710451 details
GRB7_HUMANTIE2_HUMANHPRD10521483 details
GRB7_HUMAN1433S_HUMANBioGRID, MINT15778465 details
GRB7_HUMANRASK_HUMANIntAct29290818 details
GRB7_HUMANSOS2_HUMANIntAct29290818 details
GRB7_HUMANNPM_HUMANBioGRID14968112 details
GRB7_HUMANHSP7C_HUMANBioGRID32360748 details
GRB7_HUMANCAPR1_HUMANBioGRID32360748 details
GRB7_HUMANGRB2_HUMANHPRD10377264 details
GRB7_HUMANCAV1_HUMANHPRD11075810 details
GRB7_HUMANM3K14_HUMANHPRD12853971 details