Entity Details

Primary name GTF2H4
Entity type gene
Source Source Link

Details

PrimaryID2968
RefseqGene
SymbolGTF2H4
Namegeneral transcription factor IIH subunit 4
Chromosome6
Location6p21.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTF2H4_HUMAN

GO terms

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GOName
GO:0000438 core TFIIH complex portion of holo TFIIH complex
GO:0000439 transcription factor TFIIH core complex
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0001671 ATPase activator activity
GO:0003690 double-stranded DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005669 transcription factor TFIID complex
GO:0005675 transcription factor TFIIH holo complex
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006361 transcription initiation from RNA polymerase I promoter
GO:0006363 termination of RNA polymerase I transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0016607 nuclear speck
GO:0033683 nucleotide-excision repair, DNA incision
GO:0070816 phosphorylation of RNA polymerase II C-terminal domain
GO:0070911 global genome nucleotide-excision repair

Diseases

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Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
GTF2H4GTF2H5BioGRID, DIP, IntAct19172752 24981860 26340423 26496610 28514442 32296183 details
GTF2H4EIF1ADBioGRID, IntAct32296183 details
GTF2H4EAF1BioGRID, IntAct32296183 details
GTF2H4SREK1IP1BioGRID, IntAct32296183 details
GTF2H4ERCC3BioGRID, DIP, HPRD, IntAct15220921 19172752 22939629 24981860 26340423 26344197 28514442 9118947 details
GTF2H4GTF2H3BioGRID, IntAct, MINT12080057 22939629 24981860 26340423 26344197 28514442 details
GTF2H4GTF2H2BioGRID, DIP, IntAct11062469 19172752 19934020 22939629 24981860 26340423 26344197 28977422 details
GTF2H4TBPBioGRID9159119 details
GTF2H4GTF2BBioGRID9159119 details
GTF2H4POLR2ABioGRID9159119 details
GTF2H4GTF2E1BioGRID, HPRD11113176 9159119 details
GTF2H4GTF2F1BioGRID24981860 9159119 details
GTF2H4TP53BioGRID8612585 details
GTF2H4BRCA1BioGRID9159119 details
GTF2H4MED21BioGRID9159119 details
GTF2H4BTAF1BioGRID9159119 details
GTF2H4RNF11BioGRID23751493 details
GTF2H4SHLD2BioGRID30154076 details
GTF2H4ERCC5HPRD16246722 details
GTF2H4CDK7BioGRID, IntAct17643375 23602568 29568061 details
GTF2H4CCNHBioGRID, DIP, IntAct19172752 22939629 26340423 details
GTF2H4GTF2H1BioGRID, DIP, IntAct19172752 22939629 24981860 26340423 26344197 details
GTF2H4GTF2H2CBioGRID, IntAct24981860 26344197 28514442 details
GTF2H4GTF2H2C_2BioGRID, IntAct26186194 26344197 28514442 details
GTF2H4ERCC2DIP19172752 27193682 details
GTF2H4NEURL4IntAct29426014 details
GTF2H4TP53BP1BioGRID, UniProt29656893 details
GTF2H4ESR1BioGRID, IntAct31527615 details
GTF2H4PRDM11BioGRID, MINT24981860 details
GTF2H4MNAT1BioGRID22939629 details
GTF2H4RNF4BioGRID29180619 details
GTF2H4MYCBioGRID29467282 details
GTF2H4NR2C2BioGRID30463901 details
GTF2H4ZBTB10BioGRID30629181 details
GTF2H4FKBP10BioGRID31536960 details
GTF2H4RCN2BioGRID31536960 details
GTF2H4MGARPBioGRID31536960 details
GTF2H4NUCB2BioGRID31536960 details
GTF2H4GRPEL1BioGRID31536960 details
GTF2H4PRMT2BioGRID24981860 details
GTF2H4DDRGK1BioGRID32807901 details