Entity Details

Primary name NCF4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15080
EntryNameNCF4_HUMAN
FullNameNeutrophil cytosol factor 4
TaxID9606
Evidenceevidence at protein level
Length339
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesNCF4

GO terms

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GOName
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006801 superoxide metabolic process
GO:0006909 phagocytosis
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0016175 superoxide-generating NAD(P)H oxidase activity
GO:0016176 superoxide-generating NADPH oxidase activator activity
GO:0032010 phagolysosome
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0034599 cellular response to oxidative stress
GO:0042554 superoxide anion generation
GO:0043020 NADPH oxidase complex
GO:0045454 cell redox homeostasis
GO:0045730 respiratory burst
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0060090 molecular adaptor activity

Subcellular Location

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Subcellular Location
Cytoplasm
Endosome membrane
Membrane

Domains

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DomainNameCategoryType
IPR000270 PB1 domainDomainDomain
IPR000919 Neutrophil cytosol factor P40FamilyFamily
IPR001452 SH3 domainDomainDomain
IPR001683 Phox homologyDomainDomain
IPR034853 Neutrophil cytosol factor P40, PB1 domainDomainDomain
IPR034912 Neutrophil cytosol factor 4, PX domainDomainDomain
IPR035541 Neutrophil cytosol factor P40, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036871 PX domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00514 DextromethorphanDrugbanksmall molecule