Entity Details

Primary name TMED2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15363
EntryNameTMED2_HUMAN
FullNameTransmembrane emp24 domain-containing protein 2
TaxID9606
Evidenceevidence at protein level
Length201
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesTMED2

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001843 neural tube closure
GO:0001893 maternal placenta development
GO:0001947 heart looping
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0007030 Golgi organization
GO:0010628 positive regulation of gene expression
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016021 integral component of membrane
GO:0030133 transport vesicle
GO:0030134 COPII-coated ER to Golgi transport vesicle
GO:0030137 COPI-coated vesicle
GO:0030663 COPI-coated vesicle membrane
GO:0032525 somite rostral/caudal axis specification
GO:0032580 Golgi cisterna membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0034260 negative regulation of GTPase activity
GO:0035264 multicellular organism growth
GO:0035459 vesicle cargo loading
GO:0036342 post-anal tail morphogenesis
GO:0036499 PERK-mediated unfolded protein response
GO:0042589 zymogen granule membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0048205 COPI coating of Golgi vesicle
GO:0048208 COPII vesicle coating
GO:0060716 labyrinthine layer blood vessel development
GO:0072659 protein localization to plasma membrane
GO:0090158 endoplasmic reticulum membrane organization
GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
GO:2000638 regulation of SREBP signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Cytoplasmic vesicle membrane
Endoplasmic reticulum membrane
Endoplasmic reticulum-Golgi intermediate compartment membrane
Golgi apparatus

Domains

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DomainNameCategoryType
IPR009038 GOLD domainDomainDomain
IPR015720 Transmembrane emp24 domain-containing proteinFamilyFamily
IPR036598 GOLD domain superfamilyFamilyHomologous superfamily

Diseases

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