Entity Details

Primary name USP50
Entity type gene
Source Source Link

Details

PrimaryID373509
RefseqGene
SymbolUSP50
Nameubiquitin specific peptidase 50
Chromosome15
Location15q21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-09-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsUBP50_HUMAN

GO terms

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GOName
GO:0004843 thiol-dependent deubiquitinase
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007032 endosome organization
GO:0007265 Ras protein signal transduction
GO:0014069 postsynaptic density
GO:0016579 protein deubiquitination
GO:0019783 ubiquitin-like protein-specific protease activity
GO:0019897 extrinsic component of plasma membrane
GO:0030496 midbody
GO:0031313 extrinsic component of endosome membrane
GO:0032731 positive regulation of interleukin-1 beta production
GO:0035063 nuclear speck organization
GO:0043197 dendritic spine
GO:0070536 protein K63-linked deubiquitination
GO:0071108 protein K48-linked deubiquitination
GO:1900227 positive regulation of NLRP3 inflammasome complex assembly
GO:2001056 positive regulation of cysteine-type endopeptidase activity

Diseases

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Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
USP50HSP90AB1BioGRID20930503 details
USP50HSP90AA1BioGRID20930503 details
USP50PYCARDBioGRID28094437 details
USP50HSPA8BioGRID20930503 details
USP50HSPA1ABioGRID20930503 details
USP50STING1BioGRID27801882 details
USP50NLRP3BioGRID28094437 details
USP50XRCC6BioGRID29101126 details
USP50HUWE1BioGRID, IntAct19615732 details
USP50LUC7LBioGRID, IntAct19615732 details
USP50ACADMBioGRID, IntAct19615732 details
USP50SLC25A13BioGRID, IntAct19615732 details
USP50BSGBioGRID, IntAct19615732 details
USP50UMPSBioGRID, IntAct19615732 details
USP50ALDH3A2BioGRID, IntAct19615732 details
USP50NUP205BioGRID, IntAct19615732 details
USP50ABCE1BioGRID, IntAct19615732 details
USP50MTHFD1LBioGRID, IntAct19615732 details
USP50IPO5BioGRID, IntAct19615732 details
USP50SLC1A5BioGRID, IntAct19615732 details
USP50AMBRA1BioGRID, IntAct19615732 details
USP50TUBA1ABioGRID, IntAct19615732 details
USP50AFG3L2BioGRID, IntAct19615732 details
USP50ABCD3BioGRID, IntAct19615732 details
USP50SRPRBBioGRID, IntAct19615732 details
USP50GNB2BioGRID, IntAct19615732 details
USP50DYNC2H1BioGRID, IntAct19615732 details
USP50CKAP4BioGRID, IntAct19615732 details
USP50IGF2RBioGRID, IntAct19615732 details