Entity Details

Primary name DDR2
Entity type gene
Source Source Link

Details

PrimaryID4921
RefseqGeneNG_016290
SymbolDDR2
Namediscoidin domain receptor tyrosine kinase 2
Chromosome1
Location1q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-13
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsDDR2_HUMAN

GO terms

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GOName
GO:0001503 ossification
GO:0003416 endochondral bone growth
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005518 collagen binding
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0010715 regulation of extracellular matrix disassembly
GO:0010763 positive regulation of fibroblast migration
GO:0015629 actin cytoskeleton
GO:0016324 apical plasma membrane
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0030500 regulation of bone mineralization
GO:0031214 biomineral tissue development
GO:0033674 positive regulation of kinase activity
GO:0034103 regulation of tissue remodeling
GO:0035988 chondrocyte proliferation
GO:0038062 protein tyrosine kinase collagen receptor activity
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway
GO:0043235 receptor complex
GO:0045669 positive regulation of osteoblast differentiation
GO:0045860 positive regulation of protein kinase activity
GO:0046777 protein autophosphorylation
GO:0048146 positive regulation of fibroblast proliferation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0090091 positive regulation of extracellular matrix disassembly

Diseases

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