Entity Details

Primary name P2RX4
Entity type gene
Source Source Link

Details

PrimaryID5025
RefseqGene
SymbolP2RX4
Namepurinergic receptor P2X 4
Chromosome12
Location12q24.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsP2RX4_HUMAN

GO terms

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GOName
GO:0001614 purinergic nucleotide receptor activity
GO:0001894 tissue homeostasis
GO:0002028 regulation of sodium ion transport
GO:0002931 response to ischemia
GO:0004931 extracellularly ATP-gated cation channel activity
GO:0005102 signaling receptor binding
GO:0005507 copper ion binding
GO:0005524 ATP binding
GO:0005639 integral component of nuclear inner membrane
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007596 blood coagulation
GO:0008217 regulation of blood pressure
GO:0008270 zinc ion binding
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0010614 negative regulation of cardiac muscle hypertrophy
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0019228 neuronal action potential
GO:0019233 sensory perception of pain
GO:0019722 calcium-mediated signaling
GO:0030054 cell junction
GO:0032308 positive regulation of prostaglandin secretion
GO:0033198 response to ATP
GO:0034220 ion transmembrane transport
GO:0034405 response to fluid shear stress
GO:0035590 purinergic nucleotide receptor signaling pathway
GO:0042118 endothelial cell activation
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043195 terminal bouton
GO:0043197 dendritic spine
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0044297 cell body
GO:0045296 cadherin binding
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0048266 behavioral response to pain
GO:0048471 perinuclear region of cytoplasm
GO:0048678 response to axon injury
GO:0050850 positive regulation of calcium-mediated signaling
GO:0050920 regulation of chemotaxis
GO:0050975 sensory perception of touch
GO:0051897 positive regulation of protein kinase B signaling
GO:0051899 membrane depolarization
GO:0051928 positive regulation of calcium ion transport
GO:0055117 regulation of cardiac muscle contraction
GO:0055119 relaxation of cardiac muscle
GO:0070062 extracellular exosome
GO:0070588 calcium ion transmembrane transport
GO:0071294 cellular response to zinc ion
GO:0071318 cellular response to ATP
GO:0097190 apoptotic signaling pathway
GO:0099604 ligand-gated calcium channel activity
GO:1904124 microglial cell migration
GO:1904141 positive regulation of microglial cell migration
GO:2001028 positive regulation of endothelial cell chemotaxis

Diseases

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Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
P2RX4MCM2BioGRID, IntAct21988832 details
P2RX4WNT4BioGRID, IntAct21988832 details
P2RX4KRTAP5-9BioGRID, IntAct25416956 details
P2RX4NOTCH2NLABioGRID, IntAct25416956 32296183 details
P2RX4DNAAF6BioGRID, IntAct25416956 details
P2RX4KRTAP1-1BioGRID, IntAct32296183 details
P2RX4KRTAP12-3BioGRID, IntAct32296183 details
P2RX4CDH5BioGRID, HPRD12088286 details
P2RX4CSGALNACT2BioGRID, IntAct28514442 details
P2RX4SPPL2BBioGRID, IntAct28514442 details
P2RX4TNPO3BioGRID, IntAct26186194 28514442 details
P2RX4EIF2B4BioGRID, IntAct26186194 28514442 details
P2RX4EIF2B3BioGRID, IntAct26186194 28514442 details
P2RX4EMC7BioGRID, IntAct26186194 28514442 details
P2RX4CYBC1BioGRID, IntAct26186194 28514442 details
P2RX4DNAJC19BioGRID, IntAct26186194 28514442 details
P2RX4COQ8BBioGRID, IntAct26186194 28514442 details
P2RX4GLT8D1BioGRID, IntAct28514442 details
P2RX4KCNJ8BioGRID, IntAct26186194 28514442 details
P2RX4PIGHBioGRID, IntAct26186194 28514442 details
P2RX4EIF2B1BioGRID, IntAct26186194 28514442 details
P2RX4EIF2B5BioGRID, IntAct26186194 28514442 details
P2RX4GALNT1BioGRID, IntAct26186194 28514442 details
P2RX4FAM20BBioGRID, IntAct26186194 28514442 details
P2RX4ORC4BioGRID, IntAct28514442 details
P2RX4EMC1BioGRID26186194 details
P2RX4FDFT1BioGRID26186194 details
P2RX4ARMCX3BioGRID26186194 details
P2RX4SPTLC2BioGRID26186194 details
P2RX4PGAP4BioGRID26186194 details
P2RX4HS2ST1BioGRID26186194 details
P2RX4SAAL1BioGRID26186194 details
P2RX4EIF2B2BioGRID26186194 details
P2RX4PLD6BioGRID26186194 details
P2RX4MKRN2BioGRID32460013 details