Entity Details

Primary name PKHD1
Entity type gene
Source Source Link

Details

PrimaryID5314
RefseqGeneNG_008753
SymbolPKHD1
NamePKHD1 ciliary IPT domain containing fibrocystin/polyductin
Chromosome6
Location6p12.3-p12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPKHD1_HUMAN

GO terms

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GOName
GO:0000132 establishment of mitotic spindle orientation
GO:0000775 chromosome, centromeric region
GO:0001822 kidney development
GO:0001952 regulation of cell-matrix adhesion
GO:0003382 epithelial cell morphogenesis
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005929 cilium
GO:0006874 cellular calcium ion homeostasis
GO:0008284 positive regulation of cell population proliferation
GO:0010824 regulation of centrosome duplication
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0022407 regulation of cell-cell adhesion
GO:0030155 regulation of cell adhesion
GO:0031362 anchored component of external side of plasma membrane
GO:0032006 regulation of TOR signaling
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0036064 ciliary basal body
GO:0038023 signaling receptor activity
GO:0042592 homeostatic process
GO:0043066 negative regulation of apoptotic process
GO:0045216 cell-cell junction organization
GO:0048471 perinuclear region of cytoplasm
GO:0048754 branching morphogenesis of an epithelial tube
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051271 negative regulation of cellular component movement
GO:0051660 establishment of centrosome localization
GO:0051898 negative regulation of protein kinase B signaling
GO:0060271 cilium assembly
GO:0070062 extracellular exosome
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0072686 mitotic spindle
GO:0090175 regulation of establishment of planar polarity
GO:0097731 9+0 non-motile cilium
GO:0098609 cell-cell adhesion
GO:1904036 negative regulation of epithelial cell apoptotic process
GO:1904054 regulation of cholangiocyte proliferation

Diseases

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Interactions

10 interactions