Entity Details

Primary name PPP3CB
Entity type gene
Source Source Link

Details

PrimaryID5532
RefseqGene
SymbolPPP3CB
Nameprotein phosphatase 3 catalytic subunit beta
Chromosome10
Location10q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-01-29
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPP2BB_HUMAN

GO terms

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GOName
GO:0001915 negative regulation of T cell mediated cytotoxicity
GO:0001946 lymphangiogenesis
GO:0004722 protein serine/threonine phosphatase activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005955 calcineurin complex
GO:0006468 protein phosphorylation
GO:0006470 protein dephosphorylation
GO:0007165 signal transduction
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0007507 heart development
GO:0007612 learning
GO:0007613 memory
GO:0016311 dephosphorylation
GO:0017156 calcium-ion regulated exocytosis
GO:0019899 enzyme binding
GO:0030018 Z disc
GO:0030217 T cell differentiation
GO:0030315 T-tubule
GO:0030346 protein phosphatase 2B binding
GO:0031987 locomotion involved in locomotory behavior
GO:0033173 calcineurin-NFAT signaling cascade
GO:0033192 calmodulin-dependent protein phosphatase activity
GO:0034097 response to cytokine
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042098 T cell proliferation
GO:0042110 T cell activation
GO:0043029 T cell homeostasis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0048167 regulation of synaptic plasticity
GO:0048675 axon extension
GO:0050796 regulation of insulin secretion
GO:0097720 calcineurin-mediated signaling
GO:0098978 glutamatergic synapse
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1900242 regulation of synaptic vesicle endocytosis

Diseases

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Interactions

73 interactions

InteractorPartnerSourcesPublicationsLink
PPP3CBGRB2IntAct17474147 details
PPP3CBIRF2BioGRID, IntAct21903422 details
PPP3CBTBC1D10CDIP17230191 details
PPP3CBLMTK2BioGRID, MINT28065597 details
PPP3CBAATKBioGRID, MINT28065597 details
PPP3CBEGFRBioGRID, MINT28065597 details
PPP3CBROR2BioGRID, MINT28065597 details
PPP3CBPTK7BioGRID, MINT28065597 details
PPP3CBATOH8UniProt26496921 details
PPP3CBJUNBioGRID17952113 details
PPP3CBIRAK1BioGRID21903422 details
PPP3CBMARCHF7BioGRID24905733 details
PPP3CBFBXL17BioGRID31560077 details
PPP3CBCABIN1HPRD11714752 9655484 details
PPP3CBSLC8A1HPRD15557343 details
PPP3CBCACNA1HMINT23669360 details
PPP3CBTFEBDIP25720963 details
PPP3CBMLH1BioGRID17148452 details
PPP3CBPDE4DBioGRID20647544 details
PPP3CBTRIM16BioGRID27693506 details
PPP3CBNFATC2HPRD11030334 9660947 details
PPP3CBSOCS3HPRD11970967 details
PPP3CBMYOZ2HPRD11114196 details
PPP3CBMYOZ3HPRD11842093 details
PPP3CBSLC8A2HPRD15557343 details
PPP3CBSLC8A3HPRD15557343 details
PPP3CBGABARAPL2IntAct20562859 details
PPP3CBPPP1R13BBioGRID, IntAct24366813 details
PPP3CBPPP1CCIntAct24366813 details
PPP3CBRAD51BioGRID, IntAct26496610 details
PPP3CBRBM17BioGRID, IntAct26496610 details
PPP3CBPHF5ABioGRID, IntAct26496610 details
PPP3CBCOX5ABioGRID, IntAct26496610 details
PPP3CBRSRC1BioGRID, IntAct26496610 details
PPP3CBHSPA9BioGRID, IntAct26496610 details
PPP3CBKLRG2BioGRID, IntAct28514442 details
PPP3CBPPP3CCBioGRID, IntAct26186194 28514442 details
PPP3CBPDHBBioGRID, IntAct26186194 28514442 details
PPP3CBDEFA1BioGRID, IntAct28514442 details
PPP3CBDEFA1BIntAct28514442 details
PPP3CBTMEM200ABioGRID, IntAct28514442 details
PPP3CBCDR2BioGRID, IntAct28514442 details
PPP3CBRCAN3BioGRID, IntAct26186194 27880917 28514442 details
PPP3CBRCAN2BioGRID, IntAct26186194 28514442 details
PPP3CBRCAN1BioGRID, IntAct27880917 28514442 details
PPP3CBCRTC2BioGRID, IntAct28514442 details
PPP3CBPRNPBioGRID, UniProt29791485 details
PPP3CBSH3KBP1BioGRID, IntAct31980649 details
PPP3CBGRB10BioGRID, IntAct31980649 details
PPP3CBATG7BioGRID22863883 details
PPP3CBSRSF5BioGRID22863883 details
PPP3CBVPS25BioGRID22863883 details
PPP3CBVPS36BioGRID22863883 details
PPP3CBWDR12BioGRID22863883 details
PPP3CBDNAAF10BioGRID22863883 details
PPP3CBCEP76BioGRID23443559 details
PPP3CBTUBGCP3BioGRID23443559 details
PPP3CBRASSF2BioGRID26186194 details
PPP3CBPPP1R3ABioGRID24366813 details
PPP3CBAHNAKBioGRID27880917 details
PPP3CBARMT1BioGRID27880917 details
PPP3CBCALM2BioGRID27880917 details
PPP3CBGSK3ABioGRID27880917 details
PPP3CBLBHBioGRID27880917 details
PPP3CBPI4KABioGRID27880917 details
PPP3CBPPP3R1BioGRID27880917 details
PPP3CBZYXBioGRID27880917 details
PPP3CBKRASBioGRID30639242 details
PPP3CBMYCBioGRID30415952 details
PPP3CBPLEKHA4BioGRID31091453 details
PPP3CBMAGEA3BioGRID31267705 details
PPP3CBBCAR1BioGRID33001583 details
PPP3CBELAVL1BioGRID19322201 details