Search
News
Downloads
About
Help
Contact
Entity Details
Primary name
TOP2B
Entity type
gene
Source
Source Link
Details
PrimaryID
7155
RefseqGene
NG_052961
Symbol
TOP2B
Name
DNA topoisomerase II beta
Chromosome
3
Location
3p24.2
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
1992-05-22
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
TOP2B_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0000712
resolution of meiotic recombination intermediates
GO:0000819
sister chromatid segregation
GO:0001764
neuron migration
GO:0003677
DNA binding
GO:0003682
chromatin binding
GO:0003918
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005080
protein kinase C binding
GO:0005524
ATP binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005730
nucleolus
GO:0005829
cytosol
GO:0006265
DNA topological change
GO:0007409
axonogenesis
GO:0008022
protein C-terminus binding
GO:0019899
enzyme binding
GO:0030900
forebrain development
GO:0042826
histone deacetylase binding
GO:0045870
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0046872
metal ion binding
GO:0046982
protein heterodimerization activity
GO:1990904
ribonucleoprotein complex
Diseases
Show/Hide Table
Interactions
150 interactions
Interactor
Partner
Sources
Publications
Link
TOP2B
TOPBP1
BioGRID, HPRD
9461304
details
TOP2B
HDAC1
BioGRID, HPRD
11062478
11136718
details
TOP2B
HDAC2
BioGRID
11062478
details
TOP2B
TOP2A
BioGRID, HPRD
22939629
8710863
details
TOP2B
TP53
BioGRID, HPRD
10666337
details
TOP2B
SUMO1
BioGRID, HPRD
10862613
details
TOP2B
CD3E
BioGRID, HPRD
8626450
details
TOP2B
CSNK2B
BioGRID, HPRD
11710515
details
TOP2B
RARA
BioGRID
18212063
details
TOP2B
RANBP2
BioGRID
18394993
details
TOP2B
ERG
BioGRID
24591637
details
TOP2B
UBE2I
BioGRID
10862613
15561718
details
TOP2B
SUMO2
BioGRID
19394292
details
TOP2B
LAMTOR5
BioGRID
23241634
details
TOP2B
ESR1
BioGRID, IntAct
16794079
21182205
details
TOP2B
MTA2
BioGRID
11062478
details
TOP2B
PARP1
BioGRID
16794079
34079125
details
TOP2B
SRRM1
BioGRID
16159877
details
TOP2B
PML
BioGRID
18212063
details
TOP2B
CTCF
BioGRID
19450526
details
TOP2B
RBX1
BioGRID
30349055
32015321
details
TOP2B
BECN1
BioGRID
28345663
details
TOP2B
PDCD4
BioGRID
29395067
details
TOP2B
BTRC
BioGRID
32015321
details
TOP2B
ATM
BioGRID
32015321
details
TOP2B
CSNK1D
BioGRID
32015321
details
TOP2B
ISG15
BioGRID
33024031
details
TOP2B
MAPK3
HPRD
9155018
details
TOP2B
TOP2B
HPRD
8626450
details
TOP2B
XPO1
HPRD
12821127
details
TOP2B
XRCC5
HPRD
12393188
details
TOP2B
USF1
BioGRID, IntAct
19303849
details
TOP2B
UVRAG
IntAct
20562859
details
TOP2B
CUL5
BioGRID, IntAct
21145461
28514442
details
TOP2B
PRKCD
IntAct
16611985
details
TOP2B
FOXD3
BioGRID, MINT
25609649
details
TOP2B
JUN
MINT
25609649
details
TOP2B
RPL10
BioGRID, IntAct
26496610
details
TOP2B
DAXX
BioGRID, IntAct
26496610
details
TOP2B
SPICE1
BioGRID, IntAct
26638075
details
TOP2B
CEP164
BioGRID, IntAct
26638075
details
TOP2B
NOTCH1
BioGRID, MINT
23022380
details
TOP2B
GPR75-ASB3
IntAct
28514442
details
TOP2B
ASB3
BioGRID, IntAct
28514442
details
TOP2B
PLAUR
BioGRID, IntAct
28514442
details
TOP2B
HSD3B2
BioGRID, IntAct
28514442
details
TOP2B
COX15
BioGRID, IntAct
29128334
details
TOP2B
DLST
BioGRID, IntAct
29128334
details
TOP2B
VAMP4
BioGRID, IntAct
30021884
details
TOP2B
NAPA
BioGRID, IntAct
30833792
details
TOP2B
HMGB1
BioGRID, UniProt
29721183
details
TOP2B
AKAP8L
MINT
21715506
details
TOP2B
NCBP2
IntAct
32960270
details
TOP2B
BAZ1B
BioGRID
22939629
details
TOP2B
SMARCA2
BioGRID
22939629
details
TOP2B
SMARCB1
BioGRID
22939629
details
TOP2B
SMARCC1
BioGRID
22939629
details
TOP2B
SMARCA4
BioGRID
22939629
details
TOP2B
SMARCC2
BioGRID
22939629
details
TOP2B
SMARCE1
BioGRID
22939629
details
TOP2B
SMARCD2
BioGRID
22939629
details
TOP2B
SEPTIN7
BioGRID
22939629
details
TOP2B
SFPQ
BioGRID
22939629
details
TOP2B
HNRNPR
BioGRID
22939629
details
TOP2B
NCSTN
BioGRID
22939629
details
TOP2B
SNRPE
BioGRID
22939629
details
TOP2B
RBM14
BioGRID
22939629
details
TOP2B
HDAC3
BioGRID
22939629
details
TOP2B
IK
BioGRID
22939629
details
TOP2B
MSH2
BioGRID
22939629
details
TOP2B
S100A9
BioGRID
22939629
details
TOP2B
SNRNP200
BioGRID
22939629
details
TOP2B
XPC
BioGRID
22939629
details
TOP2B
RPA1
BioGRID
24332808
details
TOP2B
RPA2
BioGRID
24332808
details
TOP2B
RPA3
BioGRID
24332808
details
TOP2B
EIF6
BioGRID
24778252
details
TOP2B
CUL7
BioGRID
24711643
details
TOP2B
OBSL1
BioGRID
24711643
details
TOP2B
GLYR1
BioGRID
26344197
details
TOP2B
POLE3
BioGRID
26344197
details
TOP2B
SUPT16H
BioGRID
26344197
details
TOP2B
TOP1
BioGRID
26344197
details
TOP2B
NTRK1
BioGRID
25921289
details
TOP2B
IFI16
BioGRID
25693804
details
TOP2B
HBP1
BioGRID
29911972
details
TOP2B
PYHIN1
BioGRID
28077445
details
TOP2B
EFTUD2
BioGRID
28515276
details
TOP2B
RNF4
BioGRID
29180619
details
TOP2B
CHD3
BioGRID
28977666
details
TOP2B
CHD4
BioGRID
28977666
details
TOP2B
EZH2
BioGRID
27634302
details
TOP2B
DCPS
BioGRID
29478914
details
TOP2B
MYC
BioGRID
29467282
details
TOP2B
GRWD1
BioGRID
29991511
details
TOP2B
ATG16L1
BioGRID
30196744
details
TOP2B
NR2C2
BioGRID
30463901
details
TOP2B
PPARG
BioGRID
30699358
details
TOP2B
XRCC6
BioGRID
30585729
details
TOP2B
H4C1
BioGRID
30804502
details
TOP2B
SNRNP70
BioGRID
29802200
details
TOP2B
BIRC3
BioGRID
30948266
details
TOP2B
STAU1
BioGRID
30948266
details
TOP2B
WWP2
BioGRID
31048545
details
TOP2B
ERCC6
BioGRID
26030138
details
TOP2B
TRIM28
BioGRID
29955894
details
TOP2B
EP300
BioGRID
30110629
details
TOP2B
PLEKHA4
BioGRID
31091453
details
TOP2B
RAD18
BioGRID
31076518
details
TOP2B
FANCD2
BioGRID
31180492
details
TOP2B
SMC3
BioGRID
31010829
details
TOP2B
PDS5A
BioGRID
31010829
details
TOP2B
MAU2
BioGRID
31010829
details
TOP2B
LRRC31
BioGRID
33005030
details
TOP2B
CIT
BioGRID
31586073
details
TOP2B
ANLN
BioGRID
31586073
details
TOP2B
CHMP4C
BioGRID
31586073
details
TOP2B
ECT2
BioGRID
31586073
details
TOP2B
KIF14
BioGRID
31586073
details
TOP2B
KIF20A
BioGRID
31586073
details
TOP2B
KIF23
BioGRID
31586073
details
TOP2B
PRC1
BioGRID
31586073
details
TOP2B
NUPR1
BioGRID
32780723
details
TOP2B
BRD4
BioGRID
32416067
details
TOP2B
RBM39
BioGRID
28302793
details
TOP2B
LGALS9
BioGRID
31995728
details
TOP2B
DNAJC8
BioGRID
33957083
details
TOP2B
TAF15
BioGRID
24981860
details
TOP2B
APEX1
BioGRID
34079125
details
TOP2B
CBX3
BioGRID
34079125
details
TOP2B
POLR1G
BioGRID
34079125
details
TOP2B
CENPA
BioGRID
34079125
details
TOP2B
COIL
BioGRID
34079125
details
TOP2B
DDX23
BioGRID
34079125
details
TOP2B
FBL
BioGRID
34079125
details
TOP2B
H2BC8
BioGRID
34079125
details
TOP2B
H3C1
BioGRID
34079125
details
TOP2B
LMNA
BioGRID
34079125
details
TOP2B
LYN
BioGRID
34079125
details
TOP2B
NIFK
BioGRID
34079125
details
TOP2B
NOP56
BioGRID
34079125
details
TOP2B
POLR1E
BioGRID
34079125
details
TOP2B
RPL31
BioGRID
34079125
details
TOP2B
RPS24
BioGRID
34079125
details
TOP2B
RPS6
BioGRID
34079125
details
TOP2B
ZNF330
BioGRID
34079125
details
TOP2B
FASN
IntAct
19303849
details
TOP2B
UNK
BioGRID
25737280
details
TOP2B
VIRMA
BioGRID
29507755
details
TOP2B
MKRN2
BioGRID
32460013
details
This website requires cookies in order to function. By using the site you are agreeing to this as outlined in our
Terms of Use
I Agree