Entity Details

Primary name DAPP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UN19
EntryNameDAPP1_HUMAN
FullNameDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
TaxID9606
Evidenceevidence at protein level
Length280
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesDAPP1

GO terms

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GOName
GO:0005543 phospholipid binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0007165 signal transduction
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035843 DAPP1, SH2 domainDomainDomain
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01863 Inositol 1,3,4,5-TetrakisphosphateDrugbanksmall molecule

Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
DAPP1_HUMANERBB3_HUMANBioGRID, MINT16273093 details
DAPP1_HUMANHS71A_HUMANBioGRID, IntAct21988832 details
DAPP1_HUMANHS71B_HUMANBioGRID, IntAct21988832 details
DAPP1_HUMANRL23_HUMANBioGRID, IntAct21988832 details
DAPP1_HUMAN3BHS7_HUMANBioGRID, IntAct21988832 details
DAPP1_HUMANFCSD2_HUMANBioGRID, IntAct21988832 details
DAPP1_HUMANMYLIP_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANWDR20_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANGSTCD_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANBACD2_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANZNHI1_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANPLAL2_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANRET7_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANCNDP2_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANT4S19_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANHUMMR_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANAPBB3_HUMANBioGRID, IntAct25814554 details
DAPP1_HUMANLRRK2_HUMANIntAct24947832 details
DAPP1_HUMANFAIM1_HUMANBioGRID, IntAct32296183 details
DAPP1_HUMANFRDA_HUMANBioGRID, IntAct32296183 32814053 details
DAPP1_HUMANLITAF_HUMANIntAct32814053 details
DAPP1_HUMANHD_HUMANIntAct32814053 details
DAPP1_HUMANSRC_HUMANHPRD11524430 details
DAPP1_HUMANBTK_HUMANHPRD11524430 details
DAPP1_HUMANLYN_HUMANHPRD11524430 details
DAPP1_HUMANPLCG1_HUMANHPRD10770799 details
DAPP1_HUMANPLCG2_HUMANHPRD10770799 details
DAPP1_HUMANM4K1_HUMANHPRD14563325 details
DAPP1_HUMANLCK_HUMANHPRD10880360 details