Entity Details

Primary name UBP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94782
EntryNameUBP1_HUMAN
FullNameUbiquitin carboxyl-terminal hydrolase 1
TaxID9606
Evidenceevidence at protein level
Length785
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesUSP1

GO terms

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GOName
GO:0001501 skeletal system development
GO:0004197 cysteine-type endopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006282 regulation of DNA repair
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008233 peptidase activity
GO:0009411 response to UV
GO:0016579 protein deubiquitination
GO:0035520 monoubiquitinated protein deubiquitination
GO:0036297 interstrand cross-link repair
GO:0042769 DNA damage response, detection of DNA damage

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolaseDomainDomain
IPR018200 Ubiquitin specific protease, conserved siteSiteConserved site
IPR028889 Ubiquitin specific protease domainDomainDomain
IPR033815 Ubiquitin specific peptidase 1DomainDomain
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
UBP1_HUMANIMA5_HUMANBioGRID, IntAct19615732 21466675 26496610 details
UBP1_HUMANPHLP1_HUMANBioGRID, IntAct19615732 22426999 24145035 27463890 27880917 28514442 details
UBP1_HUMANWDR48_HUMANBioGRID, DIP, IntAct, MINT18082604 19075014 19615732 20147293 22701671 23116119 23463011 24850727 24981860 25744535 26388029 27239033 27463890 27986371 28514442 30335599 30456385 31796584 32951278 details
UBP1_HUMANEZRI_HUMANBioGRID, IntAct23414517 details
UBP1_HUMANFACD2_HUMANBioGRID, HPRD15694335 18082604 27986371 30456385 31253762 32510829 details
UBP1_HUMANPCNA_HUMANBioGRID16531995 21768287 22987070 22989887 30456385 31796584 details
UBP1_HUMANUBC_HUMANBioGRID19075014 22195557 30456385 30576655 details
UBP1_HUMANTRAF6_HUMANBioGRID23105109 details
UBP1_HUMANPHF7_HUMANBioGRID23105109 details
UBP1_HUMANTRI46_HUMANBioGRID23105109 details
UBP1_HUMANDTX3_HUMANBioGRID23105109 details
UBP1_HUMANFZR1_HUMANBioGRID21768287 23589330 details
UBP1_HUMANUBE2K_HUMANBioGRID28270494 details
UBP1_HUMANFANCI_HUMANBioGRID27986371 30456385 32510829 details
UBP1_HUMANKLDC2_HUMANBioGRID30526872 details
UBP1_HUMANEZH2_HUMANBioGRID30425057 details
UBP1_HUMANNMRL1_HUMANBioGRID31796584 details
UBP1_HUMANPHLP2_HUMANBioGRID, IntAct19615732 27463890 27880917 details
UBP1_HUMANR51A1_HUMANBioGRID, IntAct26186194 27463890 28514442 details
UBP1_HUMANUBP1_HUMANBioGRID20147293 details
UBP1_HUMANATAD5_HUMANBioGRID20147293 21555454 details
UBP1_HUMANID2_HUMANBioGRID21925315 details
UBP1_HUMANCPNS1_HUMANBioGRID23589330 details
UBP1_HUMANAPC1_HUMANBioGRID21768287 details
UBP1_HUMANAKT1_HUMANBioGRID27097374 details
UBP1_HUMANTBK1_HUMANBioGRID29138248 details
UBP1_HUMANTRAF3_HUMANBioGRID29138248 details
UBP1_HUMANRIPK1_HUMANBioGRID29138248 details
UBP1_HUMANIMA4_HUMANBioGRID21466675 details
UBP1_HUMANIMA6_HUMANBioGRID21466675 details
UBP1_HUMANIMA8_HUMANBioGRID21466675 details
UBP1_HUMANIMB1_HUMANBioGRID21466675 details
UBP1_HUMANULK1_HUMANBioGRID30335599 details
UBP1_HUMANSNAI1_HUMANBioGRID31086816 details
UBP1_HUMANNFAT5_HUMANBioGRID31376680 details
UBP1_HUMANSHPRH_HUMANBioGRID31376680 details
UBP1_HUMANBCR_HUMANBioGRID32602291 details
UBP1_HUMANTAZ_HUMANBioGRID33114077 details
UBP1_HUMANUBB_HUMANHPRD15694335 details