Entity Details

Primary name I5P1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14642
EntryNameI5P1_HUMAN
FullNameInositol polyphosphate-5-phosphatase A
TaxID9606
Evidenceevidence at protein level
Length412
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesINPP5A

GO terms

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GOName
GO:0004445 inositol-polyphosphate 5-phosphatase activity
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030425 dendrite
GO:0042731 PH domain binding
GO:0043647 inositol phosphate metabolic process
GO:0046855 inositol phosphate dephosphorylation
GO:0046856 phosphatidylinositol dephosphorylation
GO:0048016 inositol phosphate-mediated signaling
GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
GO:1901215 negative regulation of neuron death

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000300 Inositol polyphosphate-related phosphataseDomainDomain
IPR005135 Endonuclease/exonuclease/phosphataseDomainDomain
IPR036691 Endonuclease/exonuclease/phosphatase superfamilyFamilyHomologous superfamily
IPR039737 Type I inositol 1,4,5-trisphosphate 5-phosphataseFamilyFamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
I5P1_HUMANPLEK_HUMANHPRD, MINT8999861 details
I5P1_HUMANTEAD2_HUMANBioGRID, IntAct32296183 details
I5P1_HUMAN1433Z_HUMANBioGRID, HPRD9398266 details