Entity Details

Primary name CRTC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ53ET0
EntryNameCRTC2_HUMAN
FullNameCREB-regulated transcription coactivator 2
TaxID9606
Evidenceevidence at protein level
Length693
SequenceStatuscomplete
DateCreated2008-02-05
DateModified2021-06-02

Ontological Relatives

GenesCRTC2

GO terms

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GOName
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006094 gluconeogenesis
GO:0008140 cAMP response element binding protein binding
GO:0016032 viral process
GO:0032793 positive regulation of CREB transcription factor activity
GO:0042593 glucose homeostasis
GO:0043970 histone H3-K9 acetylation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051289 protein homotetramerization
GO:0070062 extracellular exosome
GO:1901998 toxin transport

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR024783 Transducer of regulated CREB activity, N-terminalDomainDomain
IPR024784 Transducer of regulated CREB activity, middle domainDomainDomain
IPR024785 Transducer of regulated CREB activity, C-terminalDomainDomain
IPR024786 CREB-regulated transcription coactivatorFamilyFamily

Diseases

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Interactions

32 interactions

InteractorPartnerSourcesPublicationsLink
CRTC2_HUMANSIK3_HUMANHPRD, IntAct16306228 details
CRTC2_HUMANSIK1_HUMANHPRD, IntAct16306228 details
CRTC2_HUMANCBP_HUMANMINT17476304 details
CRTC2_HUMANCCD57_HUMANBioGRID, IntAct32296183 details
CRTC2_HUMANATPF2_HUMANBioGRID, IntAct32296183 details
CRTC2_HUMANSUFU_HUMANBioGRID, IntAct32296183 details
CRTC2_HUMANCREB1_HUMANBioGRID, IntAct32296183 details
CRTC2_HUMANCDC23_HUMANBioGRID, IntAct32296183 details
CRTC2_HUMANNONO_HUMANDIP18077367 details
CRTC2_HUMANSIK2_HUMANBioGRID, HPRD15454081 22462548 29211348 details
CRTC2_HUMANAAPK1_HUMANBioGRID22462548 details
CRTC2_HUMANMFHA1_HUMANBioGRID29513927 details
CRTC2_HUMAN1433B_HUMANBioGRID, HPRD, IntAct, MINT15324660 15454081 24255178 28514442 details
CRTC2_HUMANKCTD3_HUMANBioGRID, IntAct27173435 unassigned1312 details
CRTC2_HUMANCBY1_HUMANBioGRID, IntAct27173435 unassigned1312 details
CRTC2_HUMANZBT21_HUMANBioGRID, IntAct27173435 unassigned1312 details
CRTC2_HUMANLRFN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
CRTC2_HUMANKI13B_HUMANBioGRID, IntAct27173435 unassigned1312 details
CRTC2_HUMANKSR1_HUMANBioGRID, IntAct27173435 unassigned1312 details
CRTC2_HUMANGGYF1_HUMANIntActunassigned1312 details
CRTC2_HUMANCING_HUMANBioGRID, IntAct27173435 unassigned1312 details
CRTC2_HUMAN1433Z_HUMANBioGRID, HPRD, IntAct16306228 28514442 details
CRTC2_HUMAN1433T_HUMANBioGRID, IntAct15454081 17353931 23444366 28514442 details
CRTC2_HUMANATF6A_HUMANDIP19543265 details
CRTC2_HUMANITPR1_HUMANDIP22495310 details
CRTC2_HUMANCOP1_HUMANBioGRID17805301 details
CRTC2_HUMANH31_HUMANBioGRID19279000 details
CRTC2_HUMANEP300_HUMANBioGRID17476304 details
CRTC2_HUMANTRAF6_HUMANBioGRID27990298 details
CRTC2_HUMANPP2BA_HUMANBioGRID, HPRD15454081 27990298 details
CRTC2_HUMANMDM2_HUMANBioGRID27362806 details
CRTC2_HUMANSMAG2_HUMANBioGRID29395067 details