Entity Details

Primary name IYD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6PHW0
EntryNameIYD1_HUMAN
FullNameIodotyrosine deiodinase 1
TaxID9606
Evidenceevidence at protein level
Length289
SequenceStatuscomplete
DateCreated2006-04-04
DateModified2021-06-02

Ontological Relatives

GenesIYD

GO terms

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GOName
GO:0004447 iodide peroxidase activity
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006570 tyrosine metabolic process
GO:0006590 thyroid hormone generation
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0030659 cytoplasmic vesicle membrane
GO:0042403 thyroid hormone metabolic process

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasmic vesicle membrane

Domains

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DomainNameCategoryType
IPR000415 Nitroreductase-likeFamilyHomologous superfamily
IPR029479 NitroreductaseDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB03374 3,5-DiiodotyrosineDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IYD1_HUMANTRI69_HUMANBioGRID, IntAct25416956 25910212 details