Entity Details

Primary name WAPL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z5K2
EntryNameWAPL_HUMAN
FullNameWings apart-like protein homolog
TaxID9606
Evidenceevidence at protein level
Length1190
SequenceStatuscomplete
DateCreated2006-07-11
DateModified2021-06-02

Ontological Relatives

GenesWAPL

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0000775 chromosome, centromeric region
GO:0000785 chromatin
GO:0000795 synaptonemal complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0008156 negative regulation of DNA replication
GO:0009636 response to toxic substance
GO:0016032 viral process
GO:0035562 negative regulation of chromatin binding
GO:0045171 intercellular bridge
GO:0045875 negative regulation of sister chromatid cohesion
GO:0048146 positive regulation of fibroblast proliferation
GO:0051301 cell division
GO:0051983 regulation of chromosome segregation
GO:0060623 regulation of chromosome condensation
GO:0071168 protein localization to chromatin
GO:0071922 regulation of cohesin loading
GO:0072686 mitotic spindle

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR012502 WAPL domainDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR022771 Wings apart-like protein, C-terminalDomainDomain
IPR039874 Wings apart-like proteinFamilyFamily

Diseases

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Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
WAPL_HUMANXRN1_HUMANBioGRID, HPRD, IntAct15231747 details
WAPL_HUMANPDS5A_HUMANBioGRID, IntAct, UniProt17112726 17113138 20360068 21111234 26496610 31010829 details
WAPL_HUMANMTR1A_HUMANBioGRID, IntAct26514267 details
WAPL_HUMANARAP1_HUMANBioGRID21275903 details
WAPL_HUMANSUMO2_HUMANBioGRID32786267 details
WAPL_HUMANSMC3_HUMANBioGRID, IntAct, UniProt17112726 17113138 17349791 20360068 21111234 26496610 31010829 details
WAPL_HUMANSTAG1_HUMANBioGRID, DIP, IntAct, UniProt17112726 17113138 20360068 26496610 29867216 31010829 details
WAPL_HUMANSTAG2_HUMANBioGRID, DIP, IntAct, MINT, UniProt17112726 17113138 20360068 25173175 26496610 29263825 29867216 31010829 details
WAPL_HUMANPDS5B_HUMANBioGRID, IntAct, UniProt17112726 17113138 20360068 26496610 31010829 details
WAPL_HUMANRAD21_HUMANBioGRID, DIP, HPRD, IntAct, UniProt17112726 17113138 20360068 22145905 25173175 26496610 28514442 31010829 details
WAPL_HUMANSMC1A_HUMANBioGRID, DIP, IntAct, UniProt17112726 17113138 20360068 23242214 26496610 31010829 details
WAPL_HUMANCDCA5_HUMANBioGRID, IntAct26496610 31010829 details
WAPL_HUMANXRCC6_HUMANBioGRID, IntAct30021884 30585729 details
WAPL_HUMANSRRM1_HUMANBioGRID16159877 details
WAPL_HUMANNSE2_HUMANBioGRID22751501 details
WAPL_HUMANSIR6_HUMANBioGRID24169447 details
WAPL_HUMANUBP37_HUMANBioGRID26299517 details
WAPL_HUMANNIPBL_HUMANBioGRID31010829 details
WAPL_HUMANSCC4_HUMANBioGRID31010829 details
WAPL_HUMANHSP7C_HUMANBioGRID31010829 details
WAPL_HUMANPRP31_HUMANBioGRID31010829 details
WAPL_HUMANU520_HUMANBioGRID31010829 details
WAPL_HUMANU5S1_HUMANBioGRID31010829 details
WAPL_HUMANHNRH1_HUMANBioGRID31010829 details
WAPL_HUMANSF3B1_HUMANBioGRID31010829 details
WAPL_HUMANSF3B3_HUMANBioGRID31010829 details
WAPL_HUMANRBM15_HUMANBioGRID31010829 details
WAPL_HUMANDSRAD_HUMANBioGRID31010829 details
WAPL_HUMANDDX47_HUMANBioGRID31010829 details