Entity Details

Primary name NLRX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86UT6
EntryNameNLRX1_HUMAN
FullNameNLR family member X1
TaxID9606
Evidenceevidence at protein level
Length975
SequenceStatuscomplete
DateCreated2007-07-24
DateModified2021-06-02

Ontological Relatives

GenesNLRX1

GO terms

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GOName
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005886 plasma membrane
GO:0016032 viral process
GO:0030054 cell junction
GO:0032480 negative regulation of type I interferon production
GO:0032688 negative regulation of interferon-beta production
GO:0032715 negative regulation of interleukin-6 production
GO:0035556 intracellular signal transduction
GO:0039536 negative regulation of RIG-I signaling pathway
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0045824 negative regulation of innate immune response
GO:0050728 negative regulation of inflammatory response

Subcellular Location

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Subcellular Location
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR007111 NACHT nucleoside triphosphataseDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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