Entity Details

Primary name RDHE2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N3Y7
EntryNameRDHE2_HUMAN
FullNameEpidermal retinol dehydrogenase 2
TaxID9606
Evidenceevidence at protein level
Length309
SequenceStatuscomplete
DateCreated2007-10-02
DateModified2021-06-02

Ontological Relatives

GenesSDR16C5

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003714 transcription corepressor activity
GO:0004745 NAD-retinol dehydrogenase activity
GO:0005634 nucleus
GO:0005789 endoplasmic reticulum membrane
GO:0005811 lipid droplet
GO:0008134 transcription factor binding
GO:0016021 integral component of membrane
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0017053 transcription repressor complex
GO:0031065 positive regulation of histone deacetylation
GO:0035067 negative regulation of histone acetylation
GO:0042572 retinol metabolic process
GO:0042574 retinal metabolic process
GO:0043616 keratinocyte proliferation

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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