Entity Details

Primary name WN10B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00744
EntryNameWN10B_HUMAN
FullNameProtein Wnt-10b
TaxID9606
Evidenceevidence at protein level
Length389
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesWNT10B

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0002062 chondrocyte differentiation
GO:0005109 frizzled binding
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006629 lipid metabolic process
GO:0007224 smoothened signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0014835 myoblast differentiation involved in skeletal muscle regeneration
GO:0016055 Wnt signaling pathway
GO:0030182 neuron differentiation
GO:0030501 positive regulation of bone mineralization
GO:0030858 positive regulation of epithelial cell differentiation
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043065 positive regulation of apoptotic process
GO:0045165 cell fate commitment
GO:0045599 negative regulation of fat cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0048018 receptor ligand activity
GO:0048641 regulation of skeletal muscle tissue development
GO:0048741 skeletal muscle fiber development
GO:0050680 negative regulation of epithelial cell proliferation
GO:0050821 protein stabilization
GO:0050909 sensory perception of taste
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051885 positive regulation of timing of anagen
GO:0060070 canonical Wnt signaling pathway
GO:0060346 bone trabecula formation
GO:0061196 fungiform papilla development
GO:0071300 cellular response to retinoic acid
GO:0071320 cellular response to cAMP
GO:0071374 cellular response to parathyroid hormone stimulus
GO:0071425 hematopoietic stem cell proliferation
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0120163 negative regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR005817 WntFamilyFamily
IPR013302 Wnt-10 proteinFamilyFamily
IPR018161 Wnt protein, conserved siteSiteConserved site
IPR043158 Wnt, C-terminal domainFamilyHomologous superfamily

Diseases

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Interactions

3 interactions