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Entity Details
Primary name
DEDD2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q8WXF8
EntryName
DEDD2_HUMAN
FullName
DNA-binding death effector domain-containing protein 2
TaxID
9606
Evidence
evidence at protein level
Length
326
SequenceStatus
complete
DateCreated
2004-05-10
DateModified
2021-06-02
Ontological Relatives
Genes
DEDD2
GO terms
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GO
Name
GO:0003677
DNA binding
GO:0005654
nucleoplasm
GO:0005730
nucleolus
GO:0006396
RNA processing
GO:0008625
extrinsic apoptotic signaling pathway via death domain receptors
GO:0016075
rRNA catabolic process
GO:0019725
cellular homeostasis
GO:0030159
signaling receptor complex adaptor activity
GO:0030262
apoptotic nuclear changes
GO:0035556
intracellular signal transduction
GO:0045892
negative regulation of transcription, DNA-templated
GO:2001238
positive regulation of extrinsic apoptotic signaling pathway
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR001875
Death effector domain
Domain
Domain
IPR011029
Death-like domain superfamily
Family
Homologous superfamily
IPR038856
Death effector domain-containing protein
Family
Family
Diseases
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Drugs
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Interactions
14 interactions
Interactor
Partner
Sources
Publications
Link
DEDD2_HUMAN
CDK6_HUMAN
BioGRID, IntAct
22094256
details
DEDD2_HUMAN
A16L1_HUMAN
BioGRID, MINT
23376921
27273576
details
DEDD2_HUMAN
RHXF2_HUMAN
BioGRID, IntAct
20211142
details
DEDD2_HUMAN
ROAA_HUMAN
BioGRID, IntAct
20211142
details
DEDD2_HUMAN
RFOX2_HUMAN
BioGRID, IntAct
20211142
details
DEDD2_HUMAN
NR2E3_HUMAN
BioGRID, IntAct
20211142
details
DEDD2_HUMAN
CFLAR_HUMAN
BioGRID, HPRD
11741985
11965497
details
DEDD2_HUMAN
DEDD_HUMAN
BioGRID, HPRD
11965497
12527898
details
DEDD2_HUMAN
CASP8_HUMAN
BioGRID, HPRD
11965497
12527898
details
DEDD2_HUMAN
DEDD2_HUMAN
BioGRID, HPRD
11741985
11965497
12527898
details
DEDD2_HUMAN
TF3C3_HUMAN
BioGRID, HPRD
11965497
details
DEDD2_HUMAN
CDA7L_HUMAN
BioGRID
25416956
details
DEDD2_HUMAN
FMR1_HUMAN
IntAct
31413325
details
DEDD2_HUMAN
CASPA_HUMAN
BioGRID, HPRD
12527898
details
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