Entity Details

Primary name FAF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96CS3
EntryNameFAF2_HUMAN
FullNameFAS-associated factor 2
TaxID9606
Evidenceevidence at protein level
Length445
SequenceStatuscomplete
DateCreated2006-06-27
DateModified2021-06-02

Ontological Relatives

GenesFAF2

GO terms

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GOName
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005811 lipid droplet
GO:0006986 response to unfolded protein
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031625 ubiquitin protein ligase binding
GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex
GO:0034389 lipid droplet organization
GO:0035473 lipase binding
GO:0035578 azurophil granule lumen
GO:0043130 ubiquitin binding
GO:0043312 neutrophil degranulation
GO:0055102 lipase inhibitor activity

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Lipid droplet

Domains

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DomainNameCategoryType
IPR001012 UBX domainDomainDomain
IPR006577 UASDomainDomain
IPR009060 UBA-like superfamilyFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

40 interactions

InteractorPartnerSourcesPublicationsLink
FAF2_HUMANTERA_HUMANBioGRID, DIP, IntAct18711132 18775313 18835813 22119785 22350894 22466964 23665563 25078495 26389662 29599191 29997244 details
FAF2_HUMANUBE3A_HUMANBioGRID, IntAct18775313 29263404 details
FAF2_HUMANINSI1_HUMANBioGRID18835813 19815544 23720822 details
FAF2_HUMANELAV1_HUMANBioGRID19322201 23618873 details
FAF2_HUMANPSMD2_HUMANBioGRID22238364 details
FAF2_HUMANTNR6_HUMANBioGRID12372427 details
FAF2_HUMANBAG6_HUMANBioGRID23246001 23665563 26389662 details
FAF2_HUMANPLPL2_HUMANBioGRID23297223 details
FAF2_HUMANUBQL2_HUMANBioGRID24215460 30442662 details
FAF2_HUMANFAF2_HUMANBioGRID23720822 details
FAF2_HUMANNF1_HUMANBioGRID20160012 26186194 details
FAF2_HUMANUB2D1_HUMANBioGRID20160012 details
FAF2_HUMANM3K1_HUMANBioGRID25260751 details
FAF2_HUMANSMUF1_HUMANBioGRID20804422 details
FAF2_HUMANOGT1_HUMANBioGRID32994395 details
FAF2_HUMANAMFR_HUMANBioGRID, IntAct18775313 18835813 21636303 22119785 23665563 26424800 27387505 32614325 details
FAF2_HUMANHIF1A_HUMANBioGRID, IntAct18775313 details
FAF2_HUMANUBL4A_HUMANBioGRID, IntAct19615732 23246001 23665563 details
FAF2_HUMANDERL2_HUMANBioGRID, IntAct21909096 22119785 26186194 26389662 28514442 details
FAF2_HUMANUBAC2_HUMANBioGRID, IntAct22119785 23297223 26389662 26424800 28514442 31073040 details
FAF2_HUMANDERL1_HUMANBioGRID, IntAct21909096 22119785 22238364 23665563 34079125 details
FAF2_HUMANOTU1_HUMANBioGRID19818707 details
FAF2_HUMANCUL3_HUMANBioGRID18775313 details
FAF2_HUMANPPB1_HUMANBioGRID18775313 details
FAF2_HUMANAUP1_HUMANBioGRID21857022 26389662 details
FAF2_HUMANUB2J1_HUMANBioGRID20435896 details
FAF2_HUMANAPOB_HUMANBioGRID22238364 26186194 details
FAF2_HUMANUBXN6_HUMANBioGRID22337587 details
FAF2_HUMANGET4_HUMANBioGRID23665563 details
FAF2_HUMANZFN2B_HUMANBioGRID24160817 details
FAF2_HUMANUBP19_HUMANBioGRID24356957 details
FAF2_HUMANUBC_HUMANBioGRID17550899 18775313 details
FAF2_HUMANSYVN1_HUMANBioGRID26424800 details
FAF2_HUMANADT1_HUMANBioGRID26389662 details
FAF2_HUMANSTING_HUMANBioGRID29899553 details
FAF2_HUMANTRI56_HUMANBioGRID29899553 details
FAF2_HUMANLMBRL_HUMANBioGRID31073040 details
FAF2_HUMANST7_HUMANBioGRID29395067 details
FAF2_HUMANRNF26_HUMANBioGRID32614325 details
FAF2_HUMANFAF1_HUMANHPRD12372427 details