Entity Details

Primary name RNF31_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96EP0
EntryNameRNF31_HUMAN
FullNameE3 ubiquitin-protein ligase RNF31
TaxID9606
Evidenceevidence at protein level
Length1072
SequenceStatuscomplete
DateCreated2004-03-15
DateModified2021-06-02

Ontological Relatives

GenesRNF31

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005829 cytosol
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0009898 cytoplasmic side of plasma membrane
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
GO:0023035 CD40 signaling pathway
GO:0031625 ubiquitin protein ligase binding
GO:0035631 CD40 receptor complex
GO:0042802 identical protein binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ubiquitin binding
GO:0046872 metal ion binding
GO:0050852 T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0071797 LUBAC complex
GO:0097039 protein linear polyubiquitination
GO:1903955 positive regulation of protein targeting to mitochondrion

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001876 Zinc finger, RanBP2-typeDomainDomain
IPR002867 IBR domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR015940 Ubiquitin-associated domainDomainDomain
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR018997 PUB domainDomainDomain
IPR026254 E3 ubiquitin-protein ligase RNF31-likeFamilyFamily
IPR032065 E3 ubiquitin-protein ligase RNF31, UBA-like domainDomainDomain
IPR036339 PUB-like domain superfamilyFamilyHomologous superfamily
IPR036443 Zinc finger, RanBP2-type superfamilyFamilyHomologous superfamily
IPR040641 E3 ubiquitin-protein ligase RNF31, PUB domainDomainDomain
IPR041031 RNF31, C-terminalDomainDomain
IPR044066 TRIAD supradomainDomainDomain

Diseases

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Interactions

91 interactions

InteractorPartnerSourcesPublicationsLink
RNF31_HUMANATN1_HUMANBioGRID, HPRD, IntAct16713569 details
RNF31_HUMANATX1_HUMANBioGRID, HPRD, IntAct16713569 32814053 details
RNF31_HUMANGFI1B_HUMANBioGRID, HPRD, IntAct16713569 details
RNF31_HUMANHOIL1_HUMANBioGRID, DIP, HPRD, IntAct, MINT17006537 17069764 20005846 21455180 21455181 22430200 22791023 23032187 23708998 24141947 24726327 26264872 26525107 26577923 26670046 27307491 27545878 28514442 28978479 29892012 29997244 30561431 32019898 32122970 32814053 33329596 details
RNF31_HUMANNOS3_HUMANBioGRID, IntAct21163940 details
RNF31_HUMANATX7_HUMANBioGRID, IntAct21078624 details
RNF31_HUMANSMAD3_HUMANBioGRID, IntAct21988832 details
RNF31_HUMANSOCS3_HUMANBioGRID, IntAct21988832 details
RNF31_HUMANNEMO_HUMANBioGRID, DIP, IntAct, MINT19675569 21455180 21811235 23032186 23032187 23732909 23986494 24469399 26577923 28249776 29650758 30561431 30913450 details
RNF31_HUMANSHRPN_HUMANBioGRID, DIP, InnateDB, IntAct, MINT21455180 21455181 22158122 22791023 23032186 23104095 23746843 24141947 24726327 26600301 26670046 27307491 27545878 27591049 28514442 28775156 28978479 30561431 30804189 31067453 32019898 32122970 33329596 details
RNF31_HUMANTLE5_HUMANBioGRID, IntAct25416956 details
RNF31_HUMANVASN_HUMANBioGRID, IntAct25416956 details
RNF31_HUMANCCD24_HUMANBioGRID, IntAct25416956 29892012 details
RNF31_HUMANKRA92_HUMANBioGRID, IntAct25416956 29892012 details
RNF31_HUMANTSSC4_HUMANBioGRID, IntAct25416956 details
RNF31_HUMANKIF1A_HUMANBioGRID, IntAct24722188 details
RNF31_HUMANPITX1_HUMANBioGRID, IntAct24722188 details
RNF31_HUMANUB2D2_HUMANBioGRID, DIP17006537 26789245 29643511 30017913 details
RNF31_HUMANSAV1_HUMANIntAct22570112 details
RNF31_HUMANRNF31_HUMANBioGRID, IntAct24726323 27312108 27545878 29246782 29311602 29892012 30561431 details
RNF31_HUMANICAM5_HUMANIntAct32814053 details
RNF31_HUMANIDLC_HUMANIntAct32814053 details
RNF31_HUMANKLF11_HUMANIntAct32814053 details
RNF31_HUMANNUP58_HUMANIntAct32814053 details
RNF31_HUMANATX3_HUMANIntAct32814053 details
RNF31_HUMANAZI2_HUMANBioGRID21903422 details
RNF31_HUMANTRAF1_HUMANBioGRID21903422 25996949 27893701 details
RNF31_HUMANTRI25_HUMANBioGRID21292167 29117863 details
RNF31_HUMANNR0B1_HUMANBioGRID19237537 details
RNF31_HUMANNR0B2_HUMANBioGRID19237537 details
RNF31_HUMANKPCB_HUMANBioGRID17069764 details
RNF31_HUMANUB2D1_HUMANBioGRID17006537 17069764 27312108 29311602 30017913 details
RNF31_HUMANUB2D3_HUMANBioGRID17006537 21292167 21455180 29246782 30017913 32246052 details
RNF31_HUMANUBC_HUMANBioGRID17006537 20005846 21455180 22791023 23727886 23986494 24469399 24726327 25494483 26789245 28190767 28319114 28978479 29694895 30017913 30901564 details
RNF31_HUMANOTUL_HUMANBioGRID23708998 24726323 24726327 26670046 27307491 27458237 27545878 27591049 28189684 28244869 28919039 31504727 31541095 33329596 details
RNF31_HUMANTERA_HUMANBioGRID24726323 24726327 27545878 details
RNF31_HUMANKPCA_HUMANBioGRID25118570 details
RNF31_HUMANRU1C_HUMANBioGRID25416956 details
RNF31_HUMANUB2L3_HUMANBioGRID17006537 25996949 27312108 27545878 28978479 29311602 29643511 30017913 details
RNF31_HUMANSPAT2_HUMANBioGRID27307491 27458237 27545878 27591049 28189684 details
RNF31_HUMANSEPT2_HUMANBioGRID28319114 details
RNF31_HUMANHDAC6_HUMANBioGRID28319114 details
RNF31_HUMANVDAC1_HUMANBioGRID28319114 details
RNF31_HUMANTRAF6_HUMANBioGRID28319114 details
RNF31_HUMANUBE2C_HUMANBioGRID30017913 details
RNF31_HUMANUB2D4_HUMANBioGRID30017913 details
RNF31_HUMANUB2E1_HUMANBioGRID30017913 details
RNF31_HUMANUB2E2_HUMANBioGRID30017913 details
RNF31_HUMANUB2E3_HUMANBioGRID30017913 details
RNF31_HUMANUBE2K_HUMANBioGRID30017913 details
RNF31_HUMANUBE2O_HUMANBioGRID30017913 details
RNF31_HUMANUB2Q1_HUMANBioGRID30017913 details
RNF31_HUMANUB2Q2_HUMANBioGRID30017913 details
RNF31_HUMANUB2R1_HUMANBioGRID30017913 details
RNF31_HUMANUB2R2_HUMANBioGRID30017913 details
RNF31_HUMANUBE2T_HUMANBioGRID30017913 details
RNF31_HUMANUBE2W_HUMANBioGRID30017913 details
RNF31_HUMANPPIL3_HUMANBioGRID30348973 details
RNF31_HUMANSTK4_HUMANBioGRID30901564 details
RNF31_HUMANCASP1_HUMANBioGRID32122970 details
RNF31_HUMANCASP8_HUMANBioGRID32122970 details
RNF31_HUMANCASP6_HUMANBioGRID32122970 details
RNF31_HUMANATG13_HUMANBioGRID32543267 details
RNF31_HUMANTNFA_HUMANBioGRID, DIP, IntAct, MINT20005846 23032186 23032187 23732909 23746843 23955153 24726327 26670046 27307491 27545878 30420664 30561431 31898971 32019898 details
RNF31_HUMANTNAP3_HUMANBioGRID, IntAct, MINT23032186 23032187 27545878 30561431 details
RNF31_HUMANNOD2_HUMANBioGRID, IntAct22607974 23818254 26670046 27545878 details
RNF31_HUMANDDX58_HUMANBioGRID21292167 32513696 details
RNF31_HUMANRIPK2_HUMANBioGRID22607974 details
RNF31_HUMANESR1_HUMANBioGRID24441041 details
RNF31_HUMANIRAK1_HUMANBioGRID24491438 details
RNF31_HUMANMALT1_HUMANBioGRID24491438 33329596 details
RNF31_HUMANTNR5_HUMANBioGRID20614026 details
RNF31_HUMANCYLD_HUMANBioGRID26670046 27307491 27458237 27545878 27591049 28189684 details
RNF31_HUMANRIPK1_HUMANBioGRID26670046 29955050 details
RNF31_HUMANTNR1A_HUMANBioGRID26670046 27552911 27591049 30420664 details
RNF31_HUMANPDLI7_HUMANBioGRID27545878 27903798 details
RNF31_HUMANIRF7_HUMANBioGRID27903798 details
RNF31_HUMANCAR11_HUMANBioGRID27777308 33329596 details
RNF31_HUMANBCL10_HUMANBioGRID27777308 details
RNF31_HUMANTLR3_HUMANBioGRID27810922 details
RNF31_HUMANPRKN_HUMANBioGRID27348524 details
RNF31_HUMANMAVS_HUMANBioGRID27348524 details
RNF31_HUMANTIGAR_HUMANBioGRID29650758 details
RNF31_HUMANTNR1B_HUMANBioGRID29378181 details
RNF31_HUMANCFLAR_HUMANBioGRID30361438 details
RNF31_HUMANTBK1_HUMANBioGRID30420664 details
RNF31_HUMANHD_HUMANBioGRID30886048 details
RNF31_HUMANOTULL_HUMANBioGRID31056421 details
RNF31_HUMANSNX27_HUMANBioGRID31541095 details
RNF31_HUMANPACRG_HUMANBioGRID32019898 details
RNF31_HUMANSTAT1_HUMANBioGRID32123171 details