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Entity Details
Primary name
NGLY1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q96IV0
EntryName
NGLY1_HUMAN
FullName
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
TaxID
9606
Evidence
evidence at protein level
Length
654
SequenceStatus
complete
DateCreated
2006-09-05
DateModified
2021-06-02
Ontological Relatives
Genes
NGLY1
GO terms
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GO
Name
GO:0000224
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0006457
protein folding
GO:0006515
protein quality control for misfolded or incompletely synthesized proteins
GO:0006516
glycoprotein catabolic process
GO:0006517
protein deglycosylation
GO:0046872
metal ion binding
GO:0071712
ER-associated misfolded protein catabolic process
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR002931
Transglutaminase-like
Domain
Domain
IPR006588
Peptide N glycanase, PAW domain
Domain
Domain
IPR008979
Galactose-binding-like domain superfamily
Family
Homologous superfamily
IPR018997
PUB domain
Domain
Domain
IPR036339
PUB-like domain superfamily
Family
Homologous superfamily
IPR038680
PAW domain superfamily
Family
Homologous superfamily
IPR038765
Papain-like cysteine peptidase superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
20 interactions
Interactor
Partner
Sources
Publications
Link
NGLY1_HUMAN
TERA_HUMAN
BioGRID, IntAct, MINT
15362974
16807242
20414249
22119785
29540532
details
NGLY1_HUMAN
SRPK2_HUMAN
BioGRID, IntAct
23602568
details
NGLY1_HUMAN
RD23A_HUMAN
BioGRID, IntAct
22575648
25416956
31515488
32296183
details
NGLY1_HUMAN
RD23B_HUMAN
BioGRID, HPRD, IntAct
11562482
22119785
22575648
25416956
26344197
28514442
31515488
32296183
details
NGLY1_HUMAN
UBX2B_HUMAN
BioGRID, IntAct
25416956
31515488
32296183
details
NGLY1_HUMAN
TRAD1_HUMAN
BioGRID, IntAct
25416956
31515488
32296183
details
NGLY1_HUMAN
TRI54_HUMAN
BioGRID, IntAct
25416956
31515488
32296183
details
NGLY1_HUMAN
UBQL1_HUMAN
BioGRID, IntAct
25416956
31515488
32296183
details
NGLY1_HUMAN
GUCD1_HUMAN
BioGRID, IntAct
25416956
31515488
32296183
details
NGLY1_HUMAN
PAX5_HUMAN
BioGRID, IntAct
32296183
details
NGLY1_HUMAN
VMAC_HUMAN
BioGRID, IntAct
32296183
details
NGLY1_HUMAN
BICRL_HUMAN
BioGRID, IntAct
32296183
details
NGLY1_HUMAN
NPAS2_HUMAN
BioGRID, IntAct
32296183
details
NGLY1_HUMAN
PAX6_HUMAN
BioGRID, IntAct
32296183
details
NGLY1_HUMAN
HTF4_HUMAN
BioGRID, IntAct
32296183
details
NGLY1_HUMAN
FAF1_HUMAN
BioGRID
16807242
28443643
details
NGLY1_HUMAN
NSF1C_HUMAN
BioGRID
16807242
details
NGLY1_HUMAN
DERL1_HUMAN
BioGRID
16055502
details
NGLY1_HUMAN
A4_HUMAN
BioGRID
21832049
details
NGLY1_HUMAN
FMR1_HUMAN
IntAct
31413325
details
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