Entity Details

Primary name S22AC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96S37
EntryNameS22AC_HUMAN
FullNameSolute carrier family 22 member 12
TaxID9606
Evidenceevidence at protein level
Length553
SequenceStatuscomplete
DateCreated2007-10-23
DateModified2021-06-02

Ontological Relatives

GenesSLC22A12

GO terms

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GOName
GO:0005886 plasma membrane
GO:0015143 urate transmembrane transporter activity
GO:0015711 organic anion transport
GO:0015747 urate transport
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0019725 cellular homeostasis
GO:0030165 PDZ domain binding
GO:0031526 brush border membrane
GO:0042493 response to drug
GO:0046415 urate metabolic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane

Domains

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DomainNameCategoryType
IPR005828 Major facilitator, sugar transporter-likeFamilyFamily
IPR020846 Major facilitator superfamily domainDomainDomain
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00678 LosartanDrugbanksmall molecule
DB00870 SuprofenDrugbanksmall molecule
DB01032 ProbenecidDrugbanksmall molecule
DB01138 SulfinpyrazoneDrugbanksmall molecule
DB11560 LesinuradDrugbanksmall molecule
DB12466 FavipiravirDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
S22AC_HUMANNHRF3_HUMANBioGRID, HPRD14531806 details