Entity Details

Primary name SLX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BQ83
EntryNameSLX1_HUMAN
FullNameStructure-specific endonuclease subunit SLX1
TaxID9606
Evidenceevidence at protein level
Length275
SequenceStatuscomplete
DateCreated2008-04-29
DateModified2021-06-02

Ontological Relatives

GenesSLX1A
SLX1B

GO terms

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GOName
GO:0000724 double-strand break repair via homologous recombination
GO:0005654 nucleoplasm
GO:0006281 DNA repair
GO:0008821 crossover junction endodeoxyribonuclease activity
GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing
GO:0010833 telomere maintenance via telomere lengthening
GO:0017108 5'-flap endonuclease activity
GO:0033557 Slx1-Slx4 complex
GO:0036297 interstrand cross-link repair
GO:0046872 metal ion binding
GO:0061820 telomeric D-loop disassembly
GO:0090656 t-circle formation
GO:1904357 negative regulation of telomere maintenance via telomere lengthening
GO:1904431 positive regulation of t-circle formation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000305 GIY-YIG endonucleaseDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR027520 Structure-specific endonuclease subunit Slx1FamilyFamily
IPR035901 GIY-YIG endonuclease superfamilyFamilyHomologous superfamily

Diseases

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