Entity Details

Primary name RIOK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BVS4
EntryNameRIOK2_HUMAN
FullNameSerine/threonine-protein kinase RIO2
TaxID9606
Evidenceevidence at protein level
Length552
SequenceStatuscomplete
DateCreated2004-12-07
DateModified2021-06-02

Ontological Relatives

GenesRIOK2

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007049 cell cycle
GO:0030071 regulation of mitotic metaphase/anaphase transition
GO:0030490 maturation of SSU-rRNA
GO:0030688 preribosome, small subunit precursor
GO:0042274 ribosomal small subunit biogenesis
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000208 positive regulation of ribosomal small subunit export from nucleus
GO:2000234 positive regulation of rRNA processing

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000687 RIO kinaseDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR015285 RIO2 kinase winged helix domain, N-terminalDomainDomain
IPR018935 RIO kinase, conserved siteSiteConserved site
IPR030484 Serine/threonine-protein kinase Rio2DomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule