Entity Details

Primary name FZD3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NPG1
EntryNameFZD3_HUMAN
FullNameFrizzled-3
TaxID9606
Evidenceevidence at protein level
Length666
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFZD3

GO terms

Show/Hide Table
GOName
GO:0001736 establishment of planar polarity
GO:0001764 neuron migration
GO:0001843 neural tube closure
GO:0001942 hair follicle development
GO:0002052 positive regulation of neuroblast proliferation
GO:0004930 G protein-coupled receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0017147 Wnt-protein binding
GO:0030165 PDZ domain binding
GO:0030182 neuron differentiation
GO:0030424 axon
GO:0030425 dendrite
GO:0032433 filopodium tip
GO:0033278 cell proliferation in midbrain
GO:0036342 post-anal tail morphogenesis
GO:0036514 dopaminergic neuron axon guidance
GO:0036515 serotonergic neuron axon guidance
GO:0042472 inner ear morphogenesis
GO:0042493 response to drug
GO:0042813 Wnt-activated receptor activity
GO:0043025 neuronal cell body
GO:0045976 negative regulation of mitotic cell cycle, embryonic
GO:0048786 presynaptic active zone
GO:0051602 response to electrical stimulus
GO:0060070 canonical Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061549 sympathetic ganglion development
GO:0071679 commissural neuron axon guidance
GO:1900118 negative regulation of execution phase of apoptosis
GO:1904693 midbrain morphogenesis
GO:1904938 planar cell polarity pathway involved in axon guidance

Subcellular Location

Show/Hide Table
Subcellular Location
Apical cell membrane
Cell membrane
Cell surface
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR026553 Frizzled-3, vertebratesFamilyFamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR041769 Frizzled 3, cysteine-rich domainDomainDomain

Diseases

Show/Hide Table

Interactions

4 interactions