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Entity Details
Primary name
HPS4_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9NQG7
EntryName
HPS4_HUMAN
FullName
Hermansky-Pudlak syndrome 4 protein
TaxID
9606
Evidence
evidence at protein level
Length
708
SequenceStatus
complete
DateCreated
2002-06-06
DateModified
2021-06-02
Ontological Relatives
Genes
HPS4
GO terms
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GO
Name
GO:0005085
guanyl-nucleotide exchange factor activity
GO:0005737
cytoplasm
GO:0005764
lysosome
GO:0005765
lysosomal membrane
GO:0005829
cytosol
GO:0006605
protein targeting
GO:0007040
lysosome organization
GO:0007596
blood coagulation
GO:0007599
hemostasis
GO:0016020
membrane
GO:0016192
vesicle-mediated transport
GO:0030318
melanocyte differentiation
GO:0031085
BLOC-3 complex
GO:0031267
small GTPase binding
GO:0031410
cytoplasmic vesicle
GO:0042470
melanosome
GO:0042803
protein homodimerization activity
GO:0042827
platelet dense granule
GO:0046983
protein dimerization activity
GO:0048075
positive regulation of eye pigmentation
GO:0050821
protein stabilization
GO:1903232
melanosome assembly
GO:1903955
positive regulation of protein targeting to mitochondrion
Subcellular Location
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Domains
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Domain
Name
Category
Type
IPR026091
Hermansky-Pudlak syndrome 4 protein
Family
Family
IPR043987
CCZ1/INTU/HSP4, first Longin domain
Domain
Domain
IPR043989
CCZ1/INTU/HPS4, third Longin domain
Domain
Domain
Diseases
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Drugs
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Interactions
6 interactions
Interactor
Partner
Sources
Publications
Link
HPS4_HUMAN
HPS1_HUMAN
HPRD, IntAct
12756248
20048159
details
HPS4_HUMAN
RAC1_HUMAN
BioGRID, IntAct
20936779
details
HPS4_HUMAN
HPS4_HUMAN
IntAct
20048159
details
HPS4_HUMAN
RAB9A_HUMAN
IntAct
20048159
details
HPS4_HUMAN
RAB9B_HUMAN
IntAct
20048159
details
HPS4_HUMAN
DISC1_HUMAN
IntAct
31413325
details
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