Entity Details

Primary name XPP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NQW7
EntryNameXPP1_HUMAN
FullNameXaa-Pro aminopeptidase 1
TaxID9606
Evidenceevidence at protein level
Length623
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesXPNPEP1

GO terms

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GOName
GO:0004177 aminopeptidase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006508 proteolysis
GO:0010815 bradykinin catabolic process
GO:0030145 manganese ion binding
GO:0042803 protein homodimerization activity
GO:0070006 metalloaminopeptidase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000587 Creatinase, N-terminalDomainDomain
IPR000994 Peptidase M24DomainDomain
IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved siteSiteConserved site
IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminalFamilyHomologous superfamily
IPR032416 Peptidase M24, C-terminal domainDomainDomain
IPR033740 Aminopeptidase PDomainDomain
IPR036005 Creatinase/aminopeptidase-likeFamilyHomologous superfamily

Diseases

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