Entity Details

Primary name CRIM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NZV1
EntryNameCRIM1_HUMAN
FullNameCysteine-rich motor neuron 1 protein
TaxID9606
Evidenceevidence at protein level
Length1036
SequenceStatuscomplete
DateCreated2005-06-07
DateModified2021-06-02

Ontological Relatives

GenesCRIM1

GO terms

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GOName
GO:0004857 enzyme inhibitor activity
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005010 insulin-like growth factor-activated receptor activity
GO:0005520 insulin-like growth factor binding
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007399 nervous system development
GO:0016021 integral component of membrane
GO:0030165 PDZ domain binding
GO:0030514 negative regulation of BMP signaling pathway
GO:0045668 negative regulation of osteoblast differentiation

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR000867 Insulin-like growth factor-binding protein, IGFBPDomainDomain
IPR001007 VWFC domainDomainDomain
IPR004094 Antistasin-like domainDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR011061 Hirudin/antistatinFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CRIM1_HUMANATX7_HUMANBioGRID, IntAct21078624 details
CRIM1_HUMANCAC1A_HUMANBioGRID, IntAct21078624 details