Entity Details

Primary name PK2L1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9P0L9
EntryNamePK2L1_HUMAN
FullNamePolycystic kidney disease 2-like 1 protein
TaxID9606
Evidenceevidence at protein level
Length805
SequenceStatuscomplete
DateCreated2002-10-10
DateModified2021-06-02

Ontological Relatives

GenesPKD2L1

GO terms

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GOName
GO:0001581 detection of chemical stimulus involved in sensory perception of sour taste
GO:0005227 calcium activated cation channel activity
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
GO:0005272 sodium channel activity
GO:0005509 calcium ion binding
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006812 cation transport
GO:0007224 smoothened signaling pathway
GO:0008092 cytoskeletal protein binding
GO:0009415 response to water
GO:0009986 cell surface
GO:0015269 calcium-activated potassium channel activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031410 cytoplasmic vesicle
GO:0033040 sour taste receptor activity
GO:0034704 calcium channel complex
GO:0035725 sodium ion transmembrane transport
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0050912 detection of chemical stimulus involved in sensory perception of taste
GO:0050915 sensory perception of sour taste
GO:0050982 detection of mechanical stimulus
GO:0051289 protein homotetramerization
GO:0051371 muscle alpha-actinin binding
GO:0051393 alpha-actinin binding
GO:0060170 ciliary membrane
GO:0071468 cellular response to acidic pH
GO:0071805 potassium ion transmembrane transport
GO:0097730 non-motile cilium
GO:0098662 inorganic cation transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR003915 Polycystic kidney disease type 2 proteinFamilyFamily
IPR013122 Polycystin cation channel, PKD1/PKD2DomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB11093 Calcium citrateDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule