Entity Details

Primary name POLK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBT6
EntryNamePOLK_HUMAN
FullNameDNA polymerase kappa
TaxID9606
Evidenceevidence at protein level
Length870
SequenceStatuscomplete
DateCreated2005-02-15
DateModified2021-06-02

Ontological Relatives

GenesPOLK

GO terms

Show/Hide Table
GOName
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0006974 cellular response to DNA damage stimulus
GO:0016604 nuclear body
GO:0019985 translesion synthesis
GO:0033683 nucleotide-excision repair, DNA incision
GO:0034644 cellular response to UV
GO:0042276 error-prone translesion synthesis
GO:0046872 metal ion binding

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001126 UmuC domainDomainDomain
IPR006642 Rad18, zinc finger UBZ4-typeDomainDomain
IPR017961 DNA polymerase, Y-family, little finger domainDomainDomain
IPR022880 DNA polymerase IVFamilyFamily
IPR024728 DNA polymerase type-Y, HhH motifSiteConserved site
IPR036775 DNA polymerase, Y-family, little finger domain superfamilyFamilyHomologous superfamily
IPR043128 Reverse transcriptase/Diguanylate cyclase domainFamilyHomologous superfamily
IPR043502 DNA/RNA polymerase superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB07435 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENEDrugbanksmall molecule
DB07652 1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATEDrugbanksmall molecule
DB08237 2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate)Drugbanksmall molecule