Entity Details

Primary name TNF12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43508
EntryNameTNF12_HUMAN
FullNameTumor necrosis factor ligand superfamily member 12
TaxID9606
Evidenceevidence at protein level
Length249
SequenceStatuscomplete
DateCreated2002-06-06
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001938 positive regulation of endothelial cell proliferation
GO:0005102 signaling receptor binding
GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0006955 immune response
GO:0007165 signal transduction
GO:0030154 cell differentiation
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0043542 endothelial cell migration
GO:0045732 positive regulation of protein catabolic process
GO:0045766 positive regulation of angiogenesis
GO:0048018 receptor ligand activity
GO:0048471 perinuclear region of cytoplasm
GO:0097190 apoptotic signaling pathway
GO:0097191 extrinsic apoptotic signaling pathway
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR006052 Tumour necrosis factor domainDomainDomain
IPR008983 Tumour necrosis factor-like domain superfamilyFamilyHomologous superfamily

Diseases

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