Entity Details

Primary name B2L11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43521
EntryNameB2L11_HUMAN
FullNameBcl-2-like protein 11
TaxID9606
Evidenceevidence at protein level
Length198
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesBCL2L11

GO terms

Show/Hide Table
GOName
GO:0001701 in utero embryonic development
GO:0001782 B cell homeostasis
GO:0001783 B cell apoptotic process
GO:0001822 kidney development
GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0002262 myeloid cell homeostasis
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007127 meiosis I
GO:0007160 cell-matrix adhesion
GO:0007283 spermatogenesis
GO:0007420 brain development
GO:0008017 microtubule binding
GO:0008584 male gonad development
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0012505 endomembrane system
GO:0019221 cytokine-mediated signaling pathway
GO:0019898 extrinsic component of membrane
GO:0019901 protein kinase binding
GO:0030879 mammary gland development
GO:0031334 positive regulation of protein-containing complex assembly
GO:0034263 positive regulation of autophagy in response to ER overload
GO:0034976 response to endoplasmic reticulum stress
GO:0035148 tube formation
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042981 regulation of apoptotic process
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043583 ear development
GO:0045787 positive regulation of cell cycle
GO:0046620 regulation of organ growth
GO:0048066 developmental pigmentation
GO:0048070 regulation of developmental pigmentation
GO:0048536 spleen development
GO:0048538 thymus development
GO:0048563 post-embryonic animal organ morphogenesis
GO:0060139 positive regulation of apoptotic process by virus
GO:0070242 thymocyte apoptotic process
GO:0071385 cellular response to glucocorticoid stimulus
GO:0071392 cellular response to estradiol stimulus
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097136 Bcl-2 family protein complex
GO:0097140 BIM-BCL-xl complex
GO:0097141 BIM-BCL-2 complex
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1902263 apoptotic process involved in embryonic digit morphogenesis
GO:1903896 positive regulation of IRE1-mediated unfolded protein response
GO:1904646 cellular response to amyloid-beta
GO:2000271 positive regulation of fibroblast apoptotic process
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Endomembrane system
Mitochondrion

Domains

Show/Hide Table
DomainNameCategoryType
IPR014771 Apoptosis, Bim N-terminalDomainDomain
IPR015040 Bcl-x interacting, BH3 domainDomainDomain
IPR017288 Bcl-2-like protein 11FamilyFamily

Diseases

Show/Hide Table

Interactions

56 interactions

InteractorPartnerSourcesPublicationsLink
B2L11_HUMANB2CL1_HUMANBioGRID, HPRD, IntAct, MINT10198631 11859372 14596824 15694340 15721256 16260615 16697956 17289999 17525735 19427863 20836993 21199865 21671007 22516262 23245996 26186194 27013495 28514442 32296183 9430630 9731710 details
B2L11_HUMANMCL1_HUMANBioGRID, HPRD, I2D, IntAct, MINT, Molecular Connections10837489 15694340 15721256 15989957 16213503 16697956 17097560 17525735 19148187 19150432 19483105 19622586 20074640 20085765 20159608 20836993 21132008 21199865 21507240 21613222 22516262 23245996 26045051 26186194 26859456 27013495 28514442 9731710 details
B2L11_HUMANBCL2_HUMANBioGRID, HPRD, IntAct, MINT10198631 15694340 15899854 16697956 17074758 17097560 17289999 17692808 19805519 20836993 21199865 21671007 23845444 26004684 26186194 28514442 9430630 9463381 9731710 details
B2L11_HUMANB2CL2_HUMANBioGRID, HPRD, IntAct15694340 16697956 17289999 21199865 28514442 32296183 9430630 9731710 details
B2L11_HUMANAKT1_HUMANHPRD, IntAct16282323 details
B2L11_HUMAN1433B_HUMANBioGRID, HPRD, IntAct16282323 details
B2L11_HUMANB2LA1_HUMANBioGRID, HPRD, IntAct16697956 32296183 9731710 details
B2L11_HUMANBAX_HUMANBioGRID, DIP, IntAct, MINT17289999 17525735 18948948 19427863 21199865 23235460 23374347 26186194 details
B2L11_HUMANRACK1_HUMANBioGRID, IntAct18420585 details
B2L11_HUMANDYL1_HUMANBioGRID, HPRD, IntAct10198631 12591950 14561217 15193260 18420585 26186194 details
B2L11_HUMANMIF_HUMANUniProt18677096 details
B2L11_HUMANAURKB_HUMANBioGRID, IntAct21988832 details
B2L11_HUMANRIOK3_HUMANBioGRID, IntAct21988832 details
B2L11_HUMANFGL1_HUMANBioGRID, IntAct21988832 details
B2L11_HUMANVATG1_HUMANBioGRID, IntAct21988832 details
B2L11_HUMANFEM1C_HUMANBioGRID, IntAct21988832 details
B2L11_HUMANB2L11_HUMANHPRD, IntAct17289999 23374347 9731710 details
B2L11_HUMANMAGAB_HUMANBioGRID, IntAct25416956 details
B2L11_HUMANB2L10_HUMANBioGRID, IntAct23235460 32296183 details
B2L11_HUMANUSBP1_HUMANBioGRID, IntAct32296183 details
B2L11_HUMANPEX19_HUMANBioGRID, IntAct32296183 details
B2L11_HUMANMKRN3_HUMANBioGRID, IntAct32296183 details
B2L11_HUMANDTX2_HUMANBioGRID, IntAct32296183 details
B2L11_HUMANUBQL2_HUMANBioGRID, IntAct21378313 32296183 details
B2L11_HUMANPDIA1_HUMANIntAct32814053 details
B2L11_HUMANDYL2_HUMANBioGRID14561217 26186194 details
B2L11_HUMANBTK_HUMANBioGRID15096481 details
B2L11_HUMANSNF5_HUMANBioGRID15096481 details
B2L11_HUMANGTF2I_HUMANBioGRID15096481 details
B2L11_HUMANTRIM2_HUMANBioGRID21478148 details
B2L11_HUMANA4_HUMANBioGRID21832049 details
B2L11_HUMANMK08_HUMANBioGRID, HPRD12591950 12818176 details
B2L11_HUMANNDRG1_HUMANBioGRID19622774 details
B2L11_HUMANMEX3D_HUMANHPRD14769789 details
B2L11_HUMANDLRB1_HUMANMINT10198631 details
B2L11_HUMANBAD_HUMANMINT19427863 details
B2L11_HUMANKAP0_HUMANMINT21151042 details
B2L11_HUMANKAPCA_HUMANMINT21151042 details
B2L11_HUMANFBW1A_HUMANBioGRID, IntAct19150432 22388891 23912711 26186194 28514442 details
B2L11_HUMANFBW1B_HUMANBioGRID, IntAct19150432 25332235 26186194 28514442 details
B2L11_HUMANVDAC1_HUMANBioGRID, HPRD12118373 details
B2L11_HUMANHSP74_HUMANBioGRID19622774 details
B2L11_HUMANCUL2_HUMANBioGRID18420585 19622774 details
B2L11_HUMANCISH_HUMANBioGRID18420585 19622774 details
B2L11_HUMANELOB_HUMANBioGRID19622774 details
B2L11_HUMANVHL_HUMANBioGRID19305426 details
B2L11_HUMANCD302_HUMANBioGRID18420585 details
B2L11_HUMANAURKA_HUMANBioGRID23912711 details
B2L11_HUMANGIMA5_HUMANBioGRID16509771 details
B2L11_HUMANUBP27_HUMANBioGRID27013495 details
B2L11_HUMANMK01_HUMANBioGRID24269611 details
B2L11_HUMANMK03_HUMANBioGRID24269611 details
B2L11_HUMANGA45A_HUMANBioGRID15899854 details
B2L11_HUMANERN1_HUMANBioGRID31368599 details
B2L11_HUMANMK09_HUMANHPRD12818176 details
B2L11_HUMANMK10_HUMANHPRD12818176 details