Entity Details

Primary name TBX20_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UMR3
EntryNameTBX20_HUMAN
FullNameT-box transcription factor TBX20
TaxID9606
Evidenceevidence at protein level
Length447
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesTBX20

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001570 vasculogenesis
GO:0001706 endoderm formation
GO:0001708 cell fate specification
GO:0001764 neuron migration
GO:0001947 heart looping
GO:0003143 embryonic heart tube morphogenesis
GO:0003148 outflow tract septum morphogenesis
GO:0003171 atrioventricular valve development
GO:0003175 tricuspid valve development
GO:0003180 aortic valve morphogenesis
GO:0003193 pulmonary valve formation
GO:0003203 endocardial cushion morphogenesis
GO:0003207 cardiac chamber formation
GO:0003215 cardiac right ventricle morphogenesis
GO:0003272 endocardial cushion formation
GO:0003279 cardiac septum development
GO:0003344 pericardium morphogenesis
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006936 muscle contraction
GO:0008015 blood circulation
GO:0008283 cell population proliferation
GO:0009953 dorsal/ventral pattern formation
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0010991 negative regulation of SMAD protein complex assembly
GO:0014031 mesenchymal cell development
GO:0021524 visceral motor neuron differentiation
GO:0030513 positive regulation of BMP signaling pathway
GO:0035922 foramen ovale closure
GO:0036302 atrioventricular canal development
GO:0036306 embryonic heart tube elongation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048370 lateral mesoderm formation
GO:0055008 cardiac muscle tissue morphogenesis
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060413 atrial septum morphogenesis
GO:0060577 pulmonary vein morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TBX20_HUMANZSCA1_HUMANBioGRID, IntAct20211142 details