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Entity Details
Primary name
CYH3_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O43739
EntryName
CYH3_HUMAN
FullName
Cytohesin-3
TaxID
9606
Evidence
evidence at protein level
Length
400
SequenceStatus
complete
DateCreated
2001-02-21
DateModified
2021-06-02
Ontological Relatives
Genes
CYTH3
GO terms
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GO
Name
GO:0000139
Golgi membrane
GO:0001726
ruffle
GO:0005085
guanyl-nucleotide exchange factor activity
GO:0005547
phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005654
nucleoplasm
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0005912
adherens junction
GO:0005923
bicellular tight junction
GO:0031234
extrinsic component of cytoplasmic side of plasma membrane
GO:0032012
regulation of ARF protein signal transduction
GO:0045785
positive regulation of cell adhesion
GO:0048193
Golgi vesicle transport
GO:0090162
establishment of epithelial cell polarity
Subcellular Location
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Subcellular Location
Cell junction
Cell membrane
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR000904
Sec7 domain
Domain
Domain
IPR001849
Pleckstrin homology domain
Domain
Domain
IPR011993
PH-like domain superfamily
Family
Homologous superfamily
IPR023394
Sec7, C-terminal domain superfamily
Family
Homologous superfamily
IPR035999
Sec7 domain superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Drug
Name
Source
Type
DB01863
Inositol 1,3,4,5-Tetrakisphosphate
Drugbank
small molecule
DB03344
Inositol-(1,3,4,5,6)-Pentakisphosphate
Drugbank
small molecule
Interactions
13 interactions
Interactor
Partner
Sources
Publications
Link
CYH3_HUMAN
CNKR1_HUMAN
BioGRID, HPRD, IntAct
16189514
25416956
28514442
32296183
details
CYH3_HUMAN
CACO1_HUMAN
BioGRID, HPRD, IntAct
16189514
details
CYH3_HUMAN
SYCE1_HUMAN
BioGRID, IntAct
25416956
details
CYH3_HUMAN
CC120_HUMAN
BioGRID, IntAct
25416956
28514442
32296183
details
CYH3_HUMAN
ARFP2_HUMAN
BioGRID, IntAct
32296183
details
CYH3_HUMAN
IN35_HUMAN
BioGRID, IntAct
32296183
details
CYH3_HUMAN
ICEF1_HUMAN
BioGRID, IntAct
12920129
28514442
32296183
details
CYH3_HUMAN
INAVA_HUMAN
BioGRID, DIP, IntAct
28514442
29420262
30355448
details
CYH3_HUMAN
PK3CA_HUMAN
BioGRID
21041639
details
CYH3_HUMAN
GRASP_HUMAN
HPRD
10828067
details
CYH3_HUMAN
CYTIP_HUMAN
BioGRID, HPRD, IntAct
12606567
26186194
28514442
details
CYH3_HUMAN
GNAQ_HUMAN
BioGRID
17846866
details
CYH3_HUMAN
FRM4B_HUMAN
HPRD
11445584
details
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