Entity Details

Primary name COF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y281
EntryNameCOF2_HUMAN
FullNameCofilin-2
TaxID9606
Evidenceevidence at protein level
Length166
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesCFL2

GO terms

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GOName
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007519 skeletal muscle tissue development
GO:0015629 actin cytoskeleton
GO:0016363 nuclear matrix
GO:0030018 Z disc
GO:0030042 actin filament depolymerization
GO:0030043 actin filament fragmentation
GO:0030836 positive regulation of actin filament depolymerization
GO:0031674 I band
GO:0045214 sarcomere organization
GO:0046716 muscle cell cellular homeostasis
GO:0048870 cell motility
GO:0051014 actin filament severing
GO:0051015 actin filament binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus matrix

Domains

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DomainNameCategoryType
IPR002108 Actin-depolymerising factor homology domainDomainDomain
IPR017904 ADF/CofilinFamilyFamily
IPR029006 ADF-H/Gelsolin-like domain superfamilyFamilyHomologous superfamily

Diseases

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