Entity Details

Primary name RPC8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y535
EntryNameRPC8_HUMAN
FullNameDNA-directed RNA polymerase III subunit RPC8
TaxID9606
Evidenceevidence at protein level
Length204
SequenceStatuscomplete
DateCreated2003-03-28
DateModified2021-06-02

Ontological Relatives

GenesPOLR3H

GO terms

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GOName
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006139 nucleobase-containing compound metabolic process
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation from RNA polymerase III promoter
GO:0032481 positive regulation of type I interferon production
GO:0043231 intracellular membrane-bounded organelle
GO:0045087 innate immune response
GO:0051607 defense response to virus

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004519 DNA-directed RNA polymerase, subunit E/RPC8FamilyFamily
IPR005576 RNA polymerase Rpb7-like , N-terminalDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR013238 RNA polymerase III, subunit Rpc25DomainDomain
IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions